Evidence map›Paper›PMID 39941005›Full record

ArticleInternational journal of molecular sciences2025

Different Efficacy of Five Soluble Dietary Fibers on Alleviating Loperamide-Induced Constipation in Mice: Influences of Different Structural Features.

Zhiguo Zhang, Buyu Liu, Wei Liu, Xingquan Liu, Chengcheng Zhang, Weiwei Hu, Weicheng Wu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Natural Compounds for Counteracting GI and Liver Diseases.International journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Frontiers in microbiology · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhiguo ZhangFood Science Institute, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.ORCID 0000-0002-3637-8107
Buyu LiuFood Science Institute, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.ORCID 0000-0003-3704-0359
Wei LiuInstitute of Plant Protection and Microbiology, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.ORCID 0000-0002-3343-4652
Xingquan LiuCollege of Food and Health, Zhejiang Agriculture and Forestry University, Hangzhou 311300, China.
Chengcheng ZhangFood Science Institute, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Weiwei HuFood Science Institute, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Weicheng WuFood Science Institute, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.ORCID 0000-0002-5696-3354

Funding

Zhejiang National Key Research and Development Program of China 2022C02041
6 · The paper itself

Abstract

Different dietary fibers have distinct structures, leading to significant variations in their laxative effects. To explore how these structural differences impact constipation intervention, a 14-day study was conducted on loperamide-induced constipated mice using five dietary fibers: soluble dietary fiber from steamed sweet potato (SDF-S), oat β-glucan (OB), polydextrose (PD), arabinogalactan (AG), and inulin (IN). The results showed that four fibers, excluding PD, significantly improved gastrointestinal (GI) transit rate (

Indexed as

ConstipationDietary FiberLoperamideAnimalsbeta-GlucansFatty Acids, VolatileFecesGalactansGastrointestinal MicrobiomeGastrointestinal TransitGlucansInulinLaxativesMaleMicearabinogalactanbeta-GlucansDietary FiberFatty Acids, VolatileGalactansGlucansInulinLaxativesLoperamidepolydextroseconstipationdefecation functiongut microbiotashort-chain fatty acidsoluble dietary fiberstructural difference

Identifiers

PMID39941005
PMCPMC11818199

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.