Evidence map›Paper›PMID 39940926›Full record

ArticleInternational journal of molecular sciences2025

Association of Genetic Polymorphisms in SLC45A2, TYR, HERC2, and SLC24A in African Women with Melasma: A Pilot Study.

Nomakhosi Mpofana, Zinhle Pretty Mlambo, Mokgadi Ursula Makgobole, Ncoza Cordelia Dlova, Thajasvarie Naicker

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nomakhosi MpofanaDermatology Department, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban 4000, South Africa.
Zinhle Pretty MlamboDiscipline of Optics and Imaging, Doris Duke Medical Research Institute, College of Health Sciences, University of KwaZulu-Natal, Durban 4000, South Africa.
Mokgadi Ursula MakgoboleDermatology Department, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban 4000, South Africa.
Ncoza Cordelia DlovaDermatology Department, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban 4000, South Africa.
Thajasvarie NaickerDiscipline of Optics and Imaging, Doris Duke Medical Research Institute, College of Health Sciences, University of KwaZulu-Natal, Durban 4000, South Africa.ORCID 0000-0001-6917-2191

Funding

University Capacity Development Programme (UCDP), Phase 5, DHET, 2024. Phase 5, DHET, 2024
6 · The paper itself

Abstract

Melasma is a chronic skin disorder characterized by hyperpigmentation, predominantly affecting women with darker skin types, including those of African descent. This study investigates the association between genetic variants in

Indexed as

Antigens, NeoplasmAntiportersBlack PeopleFusion Regulatory Protein 1, Heavy ChainMelanosisPolymorphism, Single NucleotideUbiquitin-Protein LigasesAdultFemaleGene FrequencyGenetic Predisposition to DiseaseGenotypeHumansMembrane Transport ProteinsPilot ProjectsAntigens, NeoplasmAntiportersFusion Regulatory Protein 1, Heavy ChainHERC2 protein, humanMembrane Transport ProteinsSLC24A5 protein, humanSLC45A2 protein, humanUbiquitin-Protein Ligasesgenetic predispositionhypermelanosismelasmasingle nucleotide polymorphisms (SNPs)

Identifiers

PMID39940926
PMCPMC11818098

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.