Perspectives of Genome Editing Mediated Haploid Inducer Systems in Legumes.

Yiqian Liu, Musazade Elshan, Geng Li, Xiao Han, Xiao Chen, Xianzhong Feng

Abstract readReview

In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Yiqian LiuAgronomy College, Jilin Agricultural University, Changchun 130118, China.

Musazade ElshanKey Laboratory of Soybean Molecular Design Breeding, National Key Laboratory of Black Soils Conservation and Utilization, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Changchun 130102, China.ORCID 0000-0002-8500-8970

Geng LiKey Laboratory of Soybean Molecular Design Breeding, National Key Laboratory of Black Soils Conservation and Utilization, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Changchun 130102, China.

Xiao HanAgronomy College, Jilin Agricultural University, Changchun 130118, China.ORCID 0000-0001-8472-0109

Xiao ChenKey Laboratory of Soybean Molecular Design Breeding, National Key Laboratory of Black Soils Conservation and Utilization, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Changchun 130102, China.

Xianzhong FengKey Laboratory of Soybean Molecular Design Breeding, National Key Laboratory of Black Soils Conservation and Utilization, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Changchun 130102, China.ORCID 0000-0002-7129-3731

Funding

National Natural Science Foundation of China U21A20215

6 · The paper itself

Abstract

Genome editing-mediated haploid inducer systems (HISs) present a promising strategy for enhancing breeding efficiency in legume crops, which are vital for sustainable agriculture due to their nutritional benefits and ability to fix nitrogen. Traditional legume breeding is often slow and complicated by the complexity of legumes' genomes and the challenges associated with tissue culture. Recent advancements have broadened the applicability of HISs in legume crops, facilitating a reduction in the duration of the breeding cycle. By integrating genome editing technology with haploid breeding systems, researchers can achieve precise genetic modifications and rapidly produce homozygous lines, thereby significantly accelerating the development of desired traits. This review explores the current status and future prospects of genome editing-mediated HISs in legumes, emphasizing the mechanisms of haploid induction; recent breakthroughs; and existing technical challenges. Furthermore, we highlight the necessity for additional research to optimize these systems across various legume species, which has the potential to greatly enhance breeding efficiency and contribute to the sustainability of legume production.

Indexed as

FabaceaeGene EditingGenome, PlantHaploidyPlant BreedingCRISPR-Cas SystemsCrops, AgriculturalPlants, Genetically Modifiedgenome editinghaploid inducer lineshaploid productionlegume breeding

Identifiers

PMID39940922

DOI10.3390/ijms26031154

PMCPMC11818222

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.