Evidence map›Paper›PMID 39940830›Full record

ReviewInternational journal of molecular sciences2025

2-Guanidinobenzimidazole as Ligand in Supramolecular, Coordination and Organometallic Chemistry.

Itzia I Padilla-Martínez, Alejandro Cruz, Efrén V García-Báez

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Itzia I Padilla-MartínezLaboratorio de Química Supramolecular y Nanociencias, Departamento de Ciencias Básicas, Instituto Politécnico Nacional-UPIBI, Av. Acueducto s/n, Barrio la Laguna Ticomán, Ciudad de México 07340, Mexico.ORCID 0000-0002-9645-2049
Alejandro CruzLaboratorio de Química Supramolecular y Nanociencias, Departamento de Ciencias Básicas, Instituto Politécnico Nacional-UPIBI, Av. Acueducto s/n, Barrio la Laguna Ticomán, Ciudad de México 07340, Mexico.
Efrén V García-BáezLaboratorio de Química Supramolecular y Nanociencias, Departamento de Ciencias Básicas, Instituto Politécnico Nacional-UPIBI, Av. Acueducto s/n, Barrio la Laguna Ticomán, Ciudad de México 07340, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The benzimidazole core (BI) plays a central role in biologically active molecules. The BI nucleus is widely used as a building block to generate a variety of bioactive heterocyclic compounds to be used as antihelmintics, antiprotozoal, antimalarials, anti-inflammatories, antivirals, antimicrobials, antiparasitics, and antimycobacterials. A versatile BI derivative is the 2-guanidinobenzimidazole (2GBI), which, together with its derivatives, is a very interesting poly-functional planar molecule having a delocalised 10 π electrons system conjugated with the guanidine group. The 2GBI molecule has five nitrogen atoms containing five labile N-H bonds, which interact with the out-ward-facing channel entrance, forming a labile complex with the biological receptor sites. In this work, 2GBI and their derivatives were analyzed as ligands to form host-guest, coordination and organometallic complexes. Synthesis methodology, metal geometries, hydrogen bonding (HB) interactions, and the biological activities of the complexes were discussed.

Indexed as

BenzimidazolesCoordination ComplexesGuanidinesOrganometallic CompoundsHydrogen BondingLigandsMolecular StructureBenzimidazolesCoordination ComplexesGuanidinesLigandsOrganometallic Compounds2-guanidinobenzimidazolesbiological activity of complexesboron compoundshost–guest complexesmetallic complexesorganometallic complexes

Identifiers

PMID39940830
PMCPMC11817364

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.