Evidence map›Paper›PMID 39940804›Full record

SynthesisInternational journal of molecular sciences2025

Rationale for Testing TP53 Mutations in Thyroid Cancer-Original Data and Meta-Analysis.

Katarzyna Lacka, Adam Maciejewski, Piotr Tyburski, Ewa Manuszewska-Jopek, Przemysław Majewski, Barbara Więckowska

Abstract readMeta-Analysis
In one paragraph

Synthesis in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katarzyna LackaDepartment of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, 60-355 Poznan, Poland.ORCID 0000-0003-2386-4795
Adam MaciejewskiDepartment of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, 60-355 Poznan, Poland.ORCID 0000-0002-5381-3211
Piotr TyburskiStudent Scientific Society, Poznan University of Medical Sciences, 60-806 Poznan, Poland.ORCID 0009-0006-3371-6154
Ewa Manuszewska-JopekOutpatients Unit for Endocrine Diseases, 60-355 Poznan, Poland.
Przemysław MajewskiDepartment of Clinical Pathomorphology, Poznan University of Medical Sciences, 60-355 Poznan, Poland.
Barbara WięckowskaDepartment of Computer Science and Statistics, Poznan University of Medical Science, 60-806 Poznan, Poland.ORCID 0000-0002-1811-2583

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The p53 protein is a tumor-suppressing transcription factor that is critical in tumorigenesis. While

Indexed as

MutationThyroid Carcinoma, AnaplasticThyroid NeoplasmsTumor Suppressor Protein p53Biomarkers, TumorFemaleHumansMalePrognosisBiomarkers, TumorTP53 protein, humanTumor Suppressor Protein p53immunohistochemistrymeta-analysismutationp53thyroid cancer

Identifiers

PMID39940804
PMCPMC11817394

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.