Evidence map›Paper›PMID 39940760›Full record

ArticleInternational journal of molecular sciences2025

Brain Tumors and Beyond: Multi-Compartment Microbiome and Mycobiome Analysis.

László Sipos, Péter Banczerowski, János Juhász, Imre Fedorcsák, György Berényi, Nóra Makra, Zsuzsanna A Dunai, Dóra Szabó, Loránd Erőss

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

László SiposDepartment of Neurosurgery and Neurointervention, Semmelweis University, 1085 Budapest, Hungary.
Péter BanczerowskiDepartment of Neurosurgery and Neurointervention, Semmelweis University, 1085 Budapest, Hungary.
János JuhászInstitute of Medical Microbiology, Semmelweis University, 1089 Budapest, Hungary.ORCID 0000-0002-1307-7387
Imre FedorcsákDepartment of Neurosurgery and Neurointervention, Semmelweis University, 1085 Budapest, Hungary.
György BerényiDepartment of Neurosurgery and Neurointervention, Semmelweis University, 1085 Budapest, Hungary.
Nóra MakraInstitute of Medical Microbiology, Semmelweis University, 1089 Budapest, Hungary.
Zsuzsanna A DunaiInstitute of Medical Microbiology, Semmelweis University, 1089 Budapest, Hungary.ORCID 0009-0008-1880-429X
Dóra SzabóDepartment of Neurosurgery and Neurointervention, Semmelweis University, 1085 Budapest, Hungary.
Loránd ErőssDepartment of Neurosurgery and Neurointervention, Semmelweis University, 1085 Budapest, Hungary.

Funding

Hungarian Research Network Human Microbiota Study 0272
6 · The paper itself

Abstract

Brain tumors are frequently diagnosed diseases in which etiology and progression largely depend on mutations and genetic factors. Additionally, recent reports document that the microbiome may influence tumor growth, tumor microenvironment, and response to therapy. Our goal was to examine the extent to which the bacterial composition-microbiota-and fungal composition-mycobiota-characteristic of the tumor and its microenvironment correlate with the composition of the gut and blood microbiota and mycobiota in five randomly selected brain tumor patients. The bacterial composition of the tumor, tumor-adjacent tissue (TAT), blood, and gut samples of the five patients were analyzed by 16S rRNA and ITS-based sequencing in order to determine the bacterial and fungal composition. The gut microbiome and mycobiome composition showed individual and tissue-specific signatures in each patient. The microbiome composition of the blood, TAT, and tumor tissue was very similar in each patient, dominated by

Indexed as

Brain NeoplasmsFungiGastrointestinal MicrobiomeMicrobiotaMycobiomeAgedBacteriaFemaleHumansMaleMiddle AgedRNA, Ribosomal, 16STumor MicroenvironmentRNA, Ribosomal, 16Sbacteriabrain tumorfungigut-brain-axismicrobiomemicrobiotamycobiomemycobiotatumor microenvironment

Identifiers

PMID39940760
PMCPMC11817552

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.