Evidence map›Paper›PMID 39940730›Full record

ArticleInternational journal of molecular sciences2025

The Silkworm (

Pingyang Wang, Xiao Xiao, Ya Yang, Guiqiu Liang, Shengtao Lu, Liang Tang, Hongyan Huang, Ji He, Xiaoling Tong

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pingyang WangState Key Laboratory of Resource Insects, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, China.ORCID 0000-0003-3908-6561
Xiao XiaoGuangxi Key Laboratory of Sericultural Genetic Improvement and Efficient Breeding, Guangxi Research Academy of Sericultural Science, Guangxi Sericultural Technology Promotion Station, Nanning 530007, China.
Ya YangCollege of Sports and Health Sciences, Guangxi University for Nationalities, Nanning 530006, China.
Guiqiu LiangGuangxi Key Laboratory of Sericultural Genetic Improvement and Efficient Breeding, Guangxi Research Academy of Sericultural Science, Guangxi Sericultural Technology Promotion Station, Nanning 530007, China.
Shengtao LuCollege of Agriculture, Guangxi University, Nanning 530004, China.
Liang TangGuangxi Key Laboratory of Sericultural Genetic Improvement and Efficient Breeding, Guangxi Research Academy of Sericultural Science, Guangxi Sericultural Technology Promotion Station, Nanning 530007, China.
Hongyan HuangGuangxi Key Laboratory of Sericultural Genetic Improvement and Efficient Breeding, Guangxi Research Academy of Sericultural Science, Guangxi Sericultural Technology Promotion Station, Nanning 530007, China.
Ji HeGuangxi Key Laboratory of Sericultural Genetic Improvement and Efficient Breeding, Guangxi Research Academy of Sericultural Science, Guangxi Sericultural Technology Promotion Station, Nanning 530007, China.
Xiaoling TongState Key Laboratory of Resource Insects, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, China.ORCID 0000-0002-2649-899X

Funding

Guangxi Natural Science Foundation 2022GXNSFBA035603National Natural Science Foundation of China 32360861Opening Foundation of State Key Laboratory of Resource Insects SKLSGB-ORP202110
6 · The paper itself

Abstract

The silkworm neuropeptide Orcokinin (abbreviated as BommoOK) is equipped with multiple biological functions, one of which acts as a pigmentation inhibitor. To explore the whitening efficiency of BommoOK, the inhibitory effects on tyrosinase and its adaptability on the cell for six mature peptides of BommoOK were investigated in this paper. At the same time, BommoOKA_type4, the peptide with the best melanin inhibition effect, was used as an additive to prepare a whitening cream, and the effects on skin moisture, oil content, fine lines, skin glossiness, pores, and pigment depth were determined. The results revealed that the cream added with BommoOKA_type4 peptide showed a good improvement effect on the skin, especially in significantly reducing the pigment depths of skin. The results displayed a potential application of BommoOK in whitening and skincare products as an excellent additive and provide certain references for the mechanism research of BommoOK in inhibiting melanin synthesis.

Indexed as

BombyxNeuropeptidesSkinSkin CareSkin Lightening PreparationsSkin PigmentationAnimalsHumansMelaninsMonophenol MonooxygenaseMelaninsMonophenol MonooxygenaseNeuropeptidesSkin Lightening PreparationsmelaninneuropeptidesOrcokinintyrosinasewhitening

Identifiers

PMID39940730
PMCPMC11817372

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.