Evidence map›Paper›PMID 39940653›Full record

ReviewInternational journal of molecular sciences2025

1,3,5-Triazine: A Promising Molecular Scaffold for Novel Agents for the Treatment of Alzheimer's Disease.

Carlos F M Silva, Ana P D de M S Guerrinha, Sofia Carvalho, Diana C G A Pinto, Artur M S Silva

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carlos F M SilvaLaboratório Associado para a Química Verde-Rede de Química e Tecnologia (LAQV-REQUIMTE), Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-4538-1527
Ana P D de M S GuerrinhaLaboratório Associado para a Química Verde-Rede de Química e Tecnologia (LAQV-REQUIMTE), Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
Sofia CarvalhoLaboratório Associado para a Química Verde-Rede de Química e Tecnologia (LAQV-REQUIMTE), Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
Diana C G A PintoLaboratório Associado para a Química Verde-Rede de Química e Tecnologia (LAQV-REQUIMTE), Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-4249-7089
Artur M S SilvaLaboratório Associado para a Química Verde-Rede de Química e Tecnologia (LAQV-REQUIMTE), Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-2861-8286

Funding

Fundação para a Ciência e Tecnologia LA/P/0008/2020Fundação para a Ciência e Tecnologia UIDB/50006/2020Fundação para a Ciência e Tecnologia UIDP/50006/2020
6 · The paper itself

Abstract

Currently, Alzheimer's disease (AD) is one of the most frequent forms of dementia. From a molecular perspective, the molecular characteristics that better define this disease consist of abnormal protein deposits between neuronal cells, namely senile plaques (SPs) and neurofibrillary tangles (NFTs), consisting of protein aggregates of amyloid-

Indexed as

Alzheimer DiseaseTriazinesAmyloid beta-PeptidesAnimalsCholinesterase InhibitorsHumanstau ProteinsAmyloid beta-PeptidesCholinesterase Inhibitorstau ProteinsTriazines1,3,5-triazinesacetylcholinesteraseAlzheimer’s diseaseamyloid-βBACE-1MTDLs

Identifiers

PMID39940653
PMCPMC11817377

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.