Evidence map›Paper›PMID 39940524›Full record

ReviewPolymers2025

Advances in L-Lactic Acid Production from Lignocellulose Using Genetically Modified Microbial Systems.

Lucila Díaz-Orozco, Mario Moscosa Santillán, Rosa Elena Delgado Portales, Luis Manuel Rosales-Colunga, César Leyva-Porras, Zenaida Saavedra-Leos

Abstract readReview
In one paragraph

Review in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lucila Díaz-OrozcoFaculty of Chemical Sciences, Autonomous University of San Luis Potosí (UASLP), San Luis Potosí 78210, Mexico.
Mario Moscosa SantillánFaculty of Chemical Sciences, Autonomous University of San Luis Potosí (UASLP), San Luis Potosí 78210, Mexico.ORCID 0000-0002-1354-2963
Rosa Elena Delgado PortalesFaculty of Chemical Sciences, Autonomous University of San Luis Potosí (UASLP), San Luis Potosí 78210, Mexico.
Luis Manuel Rosales-ColungaFaculty of Engineering, Autonomous University of San Luis Potosí (UASLP), San Luis Potosí 78290, Mexico.ORCID 0000-0002-8901-4964
César Leyva-PorrasAdvanced Materials Research Center (CIMAV), Miguel de Cervantes 120, Complejo Industrial Chihuahua, Chihuahua 31136, Mexico.ORCID 0000-0003-0396-3841
Zenaida Saavedra-LeosMultidisciplinary Academic Unit, Altiplano Region Campus (COARA), Autonomous University of San Luis Potosí (UASLP), Carretera Cedral km 5+600, Matehuala 78700, Mexico.ORCID 0000-0001-6721-7114

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactic acid is a vital organic acid with a wide range of industrial applications, particularly in the food, pharmaceutical, cosmetic, and biomedical sectors. The conventional production of lactic acid from refined sugars poses high costs and significant environmental impacts, leading to the exploration of alternative raw materials and more sustainable processes. Lignocellulosic biomass, particularly agro-industrial residues such as agave bagasse, represents a promising substrate for lactic acid production. Agave bagasse, a by-product of the tequila and mezcal industries, is rich in fermentable carbohydrates, making it an ideal raw material for biotechnological processes. The use of lactic acid bacteria (LAB), particularly genetically modified microorganisms (GMMs), has been shown to enhance fermentation efficiency and lactic acid yield. This review explores the potential of lignocellulosic biomass as a substrate for microbial fermentation to produce lactic acid and other high-value products. It covers the composition and pretreatment of some agricultural residues, the selection of suitable microorganisms, and the optimization of fermentation conditions. The paper highlights the promising future of agro-industrial residue valorization through biotechnological processes and the sustainable production of lactic acid as an alternative to conventional methods.

Indexed as

agricultural residuesgenetically modified microorganismslactic acid productionlignocellulosic biomasssustainable biotechnological processes

Identifiers

PMID39940524
PMCPMC11820014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.