Evidence map›Paper›PMID 39940459›Full record

ArticlePolymers2025

Enhancing Bone Regeneration Using Blended Poly(L-lactide-co-D, L-lactide) and β-Tricalcium Phosphate Nanofibrous Periodontal Biodegradable Membranes.

Princess Joy Naig, Zih-Yin Kuo, Min-Fan Chung, Chih-Hao Chen, Chi-Yun Wang, Kuo-Yung Hung

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Princess Joy NaigDepartment of Biomedical Engineering and Medical Devices, Ming Chi University of Technology, New Taipei City 24301, Taiwan.
Zih-Yin KuoResearch Center for Intelligent Medical Devices, Ming Chi University of Technology, New Taipei City 24301, Taiwan.
Min-Fan ChungNAN YA Plastics Corporation, Plastics 1st Division, New Taipei City 238, Taiwan.
Chih-Hao ChenDepartment of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital at Keelung, Keelung 204, Taiwan.ORCID 0000-0001-7213-2596
Chi-Yun WangDepartment of Biomedical Engineering and Medical Devices, Ming Chi University of Technology, New Taipei City 24301, Taiwan.
Kuo-Yung HungResearch Center for Intelligent Medical Devices, Ming Chi University of Technology, New Taipei City 24301, Taiwan.

Funding

NAN YA Plastics Corporation I01-111-E05
6 · The paper itself

Abstract

In regenerative periodontal treatment, barrier membranes restore periodontal support and aid tissue healing, but slow hard tissue regeneration can disrupt healing and cause tooth instability. This study aimed to fabricate a periodontal membrane through electrospinning poly(L-lactide-co-D, L-lactide) with varying β-tricalcium phosphate (β-TCP) percentages (0%, 10%, 30%, and 40%) treated with hyaluronic acid to enhance bone regeneration in alveolar bone defects. Their ability to promote biomimetic mineralization was characterized using field emission scanning electron microscopy (FESEM) analysis, wettability, and mechanical properties. Biocompatibility and osteogenic differentiation were evaluated by examining BMSCs' behavior. In vivo, the PLA/β-TCP membrane's potential to promote bone regeneration was assessed through CT imaging and histological examination. FESEM analysis revealed β-TCP agglomerations within PLA fibers, increasing tensile strength. Water contact angle measurements showed better wettability and higher cell viability after hyaluronic acid treatment, indicating non-cytotoxicity. Membranes with 10% and 30% (

Indexed as

and bone regenerationbarrier membranebiodegradable polymerselectrospinningpoly(L-lactide-co-D, L-lactide)sustainable materialsβ-tricalcium phosphate

Identifiers

PMID39940459
PMCPMC12128702

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.