Evidence map›Paper›PMID 39940452›Full record

ReviewNutrients2025

Perspectives on Diet and Exercise Interaction for Healthy Aging: Opportunities to Reduce Malnutrition Risk and Optimize Fitness.

Ana Moradell, Jose Antonio Casajús, Luis A Moreno, Germán Vicente-Rodríguez

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ana MoradellGrowth, Exercise, Nutrition and Development (GENUD) Research Group (NUTRI-GENUD B34_23R; EXER-GENUD S72_23R), Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0003-0330-5558
Jose Antonio CasajúsGrowth, Exercise, Nutrition and Development (GENUD) Research Group (NUTRI-GENUD B34_23R; EXER-GENUD S72_23R), Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-7215-6931
Luis A MorenoGrowth, Exercise, Nutrition and Development (GENUD) Research Group (NUTRI-GENUD B34_23R; EXER-GENUD S72_23R), Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0003-0454-653X
Germán Vicente-RodríguezGrowth, Exercise, Nutrition and Development (GENUD) Research Group (NUTRI-GENUD B34_23R; EXER-GENUD S72_23R), Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-4303-4097

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nutrition and exercise play a pivotal role in counteracting the effects of aging, promoting health, and improving physical fitness in older adults. This perspective study examines their interplay, highlighting their combined potential to preserve muscle mass, cognitive function, and quality of life. The objective is to address gaps in the current understanding, such as the frequent neglect of dietary intake in exercise interventions and vice versa, which can limit their effectiveness. Through a synthesis of the existing literature, we identify key findings, emphasizing the importance of adequate nutritional intake-particularly protein, essential amino acids, and micronutrients-in supporting exercise benefits and preventing sarcopenia and malnutrition. Additionally, supplementation strategies, such as omega-3 fatty acids, creatine, and essential amino acids, are explored alongside the emerging role of the gut microbiota in mediating the benefits of nutrition and exercise. Despite these advances, challenges remain, including determining optimal dosages and timing and addressing individual variability in responses. Personalized approaches tailored to sex differences, gut microbiota diversity, and baseline health conditions are critical for maximizing intervention outcomes. Our conclusions underscore the necessity of integrated strategies that align dietary and exercise interventions to support healthy and active aging. By addressing these gaps, future research can provide actionable insights to optimize health and quality of life in older populations.

Indexed as

AgingDietExerciseHealthy AgingMalnutritionPhysical FitnessAgedDietary SupplementsFemaleGastrointestinal MicrobiomeHumansMaleNutritional StatusQuality of LifeSarcopeniadietary habitsgut microbiotamulticomponent trainingproteinsarcopenia

Identifiers

PMID39940452
PMCPMC11820707

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.