Evidence map›Paper›PMID 39940443›Full record

ArticleNutrients2025

The Impact of a Commercial Electrolyte Beverage on the Hydration Status of Active Men and Women.

Cary Boyd-Shiwarski, Evan Ray, Harikesh Subramanian, Nicole Zharichenko, Amy Monroe, Aman Mahajan

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cary Boyd-ShiwarskiDepartment of Medicine, Renal and Electrolyte Division, University of Pittsburgh, Pittsburgh, PA 15260, USA.ORCID 0000-0002-2350-3052
Evan RayDepartment of Medicine, Renal and Electrolyte Division, University of Pittsburgh, Pittsburgh, PA 15260, USA.ORCID 0000-0003-1491-4869
Harikesh SubramanianDepartment of Anesthesiology and Perioperative Medicine, University of Pittsburgh, University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA 15260, USA.ORCID 0000-0002-1845-0865
Nicole ZharichenkoDepartment of Anesthesiology and Perioperative Medicine, University of Pittsburgh, University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA 15260, USA.
Amy MonroeDepartment of Anesthesiology and Perioperative Medicine, University of Pittsburgh, University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA 15260, USA.
Aman MahajanDepartment of Anesthesiology and Perioperative Medicine, University of Pittsburgh, University of Pittsburgh Medical Center (UPMC), Pittsburgh, PA 15260, USA.

Funding

Regulation of Renal Tubular Mg2+ Handling by MUC1 and LactationR01DK139177 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Evan Cross Ray · 2025 to 2026
$1.2M
Establishing new model systems to study low potassium induced kidney injuryR03DK138215 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BOYD-SHIWARSKI, CARY RAGAN · 2024 to 2025
$222k
NIDDK NIH HHS R01 DK139177NIDDK NIH HHS R03 DK138215University of Pittsburgh Medical Center Department of Anesthesiology
6 · The paper itself

Abstract

BACKGROUND/

objectivesHypo-hydration is a major health concern that affects performance and is associated with increasing morbidity and growing health care costs. There is an emerging interest in optimizing hydration and identifying how factors such as ingestion rate and beverage composition affect hydration. This study examined three beverages with varying ingestion rates and measured markers of hydration.

methodsThirty healthy, active participants between the ages of 18 and 45 years were given three different beverages on three separate days. The beverages were of identical volumes (1 L), but differed in the rate of ingestion, carbohydrate content and electrolyte content. Beverage 1 and water alone were both consumed at a metered rate of one liter over four hours, whereas Beverage 2 was used as a positive control and was consumed at a bolus rate of one liter in 30 min.

resultsAfter six hours, Beverage 1 significantly improved markers of hydration compared to water alone or Beverage 2. Beverage 1 decreased cumulative urine output vs. water alone by 32% (absolute difference -0.33 L; CI ± -0.16 to -0.51) and vs. Beverage 2 by 26% (absolute difference -0.26 L; CI ± -0.13 to -0.38). Beverage 1 increased the beverage hydration index vs. water alone by 64% (absolute difference +0.64 L; CI ± 0.36 to 0.92) and vs. Beverage 2 by 48% (absolute difference +0.53 L; CI ± 0.30 to 0.76).

conclusionsBeverage 1 is superior to water alone at improving hydration when it is ingested at similar rates. Moreover, metered ingestion of Beverage 1 improved hydration compared to a bolus ingestion of Beverage 2, this could be due to the dissimilar ingestion rates and/or beverage composition.

Indexed as

BeveragesDehydrationDrinkingElectrolytesOrganism Hydration StatusWater-Electrolyte BalanceAdolescentAdultFemaleHumansMaleMiddle AgedYoung AdultElectrolytesbody hydration indexdehydrationelectrolytesrenalsupplement

Identifiers

PMID39940443
PMCPMC11820625

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.