Evidence map›Paper›PMID 39940425›Full record

ArticleNutrients2025

Dairy Consumption and the Colonic Mucosa-Associated Gut Microbiota in Humans-A Preliminary Investigation.

Ellie Chen, Nadim J Ajami, Donna L White, Yanhong Liu, Shawn Gurwara, Kristi Hoffman, David Y Graham, Hashem B El-Serag, Joseph F Petrosino, Li Jiao

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ellie ChenDepartment of Medicine, Baylor College of Medicine (BCM), Houston, TX 77030, USA.
Nadim J AjamiThe Alkek Center for Metagenomics and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine (BCM), Houston, TX 77030, USA.
Donna L WhiteDepartment of Medicine, Baylor College of Medicine (BCM), Houston, TX 77030, USA.
Yanhong LiuDepartment of Medicine, Baylor College of Medicine (BCM), Houston, TX 77030, USA.
Shawn GurwaraDepartment of Medicine, Baylor College of Medicine (BCM), Houston, TX 77030, USA.
Kristi HoffmanThe Alkek Center for Metagenomics and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine (BCM), Houston, TX 77030, USA.
David Y GrahamDepartment of Medicine, Baylor College of Medicine (BCM), Houston, TX 77030, USA.ORCID 0000-0002-6908-8317
Hashem B El-SeragDepartment of Medicine, Baylor College of Medicine (BCM), Houston, TX 77030, USA.
Joseph F PetrosinoThe Alkek Center for Metagenomics and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine (BCM), Houston, TX 77030, USA.
Li JiaoDepartment of Medicine, Baylor College of Medicine (BCM), Houston, TX 77030, USA.ORCID 0000-0002-0237-0262

Funding

Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Hashem B El-Serag · 2001 to 2026
$28.3M
Translational Research Support CoreP30ES030285 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Cheryl L. Walker · 2019 to 2026
$14.7M
Lung Cancer Prediction Models Incorporating Exome Data from Extreme PhenotypesK07CA181480 · NCI · BAYLOR COLLEGE OF MEDICINE · PI LIU, YANHONG · 2014 to 2017
$511k
Evaluating Etiological Impact of Metatranscriptomic and Immunological Features for Lung CancerR03CA262911 · NCI · BAYLOR COLLEGE OF MEDICINE · PI LIU, YANHONG · 2021 to 2022
$160k
Cancer Prevention and Research Institute of Texas RP#140767CSRD VA I01 CX001430Gillson Longenbaugh Foundation 001NCI NIH HHS K07 CA181480NCI NIH HHS R03 CA262911NIDDK NIH HHS DK56338NIDDK NIH HHS P30 DK056338NIEHS NIH HHS P30 ES030285U.S. Department of Veterans Affairs CX001430
6 · The paper itself

Abstract

backgroundDairy consumption has been associated with various health outcomes that may be mediated by changes in gut microbiota.

methodsThis cross-sectional study investigated the association between the colonic mucosa-associated gut microbiota and the self-reported intake of total dairy, milk, cheese, and yogurt. A total of 97 colonic mucosal biopsies collected from 34 polyp-free individuals were analyzed. Dairy consumption in the past year was assessed using a food frequency questionnaire. The 16S rRNA gene V4 region was amplified and sequenced. Operational taxonomic unit (OTU) classification was performed using the UPARSE and SILVA databases. OTU diversity and relative abundance were compared between lower vs. higher dairy consumption groups. Multivariable negative binomial regression models for panel data were used to estimate the incidence rate ratio and 95% confidence interval for bacterial counts and dairy consumption. False discovery rate-adjusted

resultsHigher total dairy and milk consumption and lower cheese consumption were associated with higher alpha microbial diversity (adjusted

conclusionsDairy consumption may influence host health by modulating the structure and composition of the colonic adherent gut microbiota.

Indexed as

ColonDairy ProductsDietGastrointestinal MicrobiomeIntestinal MucosaAdultAgedAnimalsBacteriaCheeseCross-Sectional StudiesFemaleHumansMaleMiddle AgedRNA, Ribosomal, 16SRNA, Ribosomal, 16SAkkermansiacheesedietFaecalibacteriumlactosemicrobiomemilknutrition

Identifiers

PMID39940425
PMCPMC11820694

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.