Evidence map›Paper›PMID 39940411›Full record

Trial reportNutrients2025

Improving Irritable Bowel Syndrome (IBS) Symptoms and Quality of Life with Quebracho and Chestnut Tannin-Based Supplementation: A Single-Centre, Randomised, Double-Blind, Placebo-Controlled Clinical Trial.

Silvia Molino, Lorenza Francesca De Lellis, Maria Vittoria Morone, Marcello Cordara, Danaè S Larsen, Roberto Piccinocchi, Gaetano Piccinocchi, Alessandra Baldi, Alessandro Di Minno, Hesham R El-Seedi and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Silvia MolinoR&D Unit, Silvateam S.p.A., 12080 San Michele Mondovì, Italy.ORCID 0000-0001-9405-5085
Lorenza Francesca De LellisDepartment of Pharmacy, University of Naples "Federico II", Via D. Montesano 49, 80131 Naples, Italy.
Maria Vittoria MoroneDepartment of Experimental Medicine, Section of Microbiology and Clinical Microbiology, University of Campania "L. Vanvitelli", 80138 Naples, Italy.ORCID 0009-0000-0810-8460
Marcello CordaraSchool of Medicine, University of Milano-Bicocca, 20126 Milan, Italy.
Danaè S LarsenSchool of Chemical Sciences, The University of Auckland, Auckland 1010, New Zealand.ORCID 0000-0002-6942-814X
Roberto PiccinocchiLevel 1 Medical Director Anaesthesia and Resuscitation A. U. O. Luigi Vanvitelli, Via Santa Maria di Costantinopoli, 80138 Naples, Italy.
Gaetano PiccinocchiComegen S.c.S., Società Cooperativa Sociale di Medici di Medicina Generale, Viale Maria Bakunin 41, 80125 Naples, Italy.ORCID 0000-0002-3095-2198
Alessandra BaldiDepartment of Pharmacy, University of Naples "Federico II", Via D. Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-2877-9445
Alessandro Di MinnoDepartment of Pharmacy, University of Naples "Federico II", Via D. Montesano 49, 80131 Naples, Italy.ORCID 0000-0001-8084-9976
Hesham R El-SeediDepartment of Chemistry, Faculty of Science, Islamic University of Madinah, Madinah 42351, Saudi Arabia.ORCID 0000-0002-2519-6690
Roberto SacchiApplied Statistic Unit, Department of Earth and Environmental Sciences, University of Pavia, Viale Taramelli 24, 27100 Pavia, Italy.ORCID 0000-0002-6199-0074
Maria DagliaDepartment of Pharmacy, University of Naples "Federico II", Via D. Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-4870-7713

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Dietary SupplementsIrritable Bowel SyndromeQuality of LifeTanninsAdolescentAdultAgedDiarrheaDouble-Blind MethodFemaleHumansMaleMiddle AgedNutsSurveys and QuestionnairesTreatment OutcomeTanninschestnutfood supplementIBSS scoreirritable bowel syndromequebrachoquestionnaire for self-assessment of quality of liferandomised clinical trialtannins

Identifiers

PMID39940411
PMCPMC11820850

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.