Evidence map›Paper›PMID 39940369›Full record

ReviewNutrients2025

Breastfeeding and Non-Communicable Diseases: A Narrative Review.

Maria Elena Capra, Valentina Aliverti, Arianna Maria Bellani, Martina Berzieri, Anna Giuseppina Montani, Gianlorenzo Pisseri, Tullia Sguerso, Susanna Esposito, Giacomo Biasucci

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maria Elena CapraPediatrics and Neonatology Unit, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy.ORCID 0000-0003-0848-5228
Valentina AlivertiPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Arianna Maria BellaniPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Martina BerzieriPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Anna Giuseppina MontaniPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Gianlorenzo PisseriPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Tullia SguersoPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Susanna EspositoPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0003-4103-2837
Giacomo BiasucciPediatrics and Neonatology Unit, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy.ORCID 0000-0002-7441-9248

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBreastfeeding plays a fundamental role in newborns' and infants' health. Breast milk's protective power against malnutrition and its positive effect on neurological and physical development are well established and are reflected in the policy statements of all major pediatric health entities. However, breastfeeding also plays an important role in the prevention of so-called non-communicable diseases, such as obesity, hypertension, dyslipidemia, and autoimmune diseases.

methodsThis narrative review aims to analyze the effect of breastfeeding and breast milk on the development of non-communicable diseases, with a special focus on weight excess, dyslipidemia, allergy, and gastrointestinal diseases. This narrative review was carried out through three steps: executing the search, examining abstracts and full texts, and analyzing results. To achieve this, the databases PubMed, EMBASE, Scopus, ScienceDirect, Web of Science, and Google Scholar were explored to collect and select publications from 1990 to 2024 to find pertinent studies in line with this review's development. The search included randomized placebo-controlled trials, controlled clinical trials, double-blind, randomized controlled studies, and systematic reviews. A total of 104 manuscripts were ultimately included in the analysis.

resultsBreastfeeding is associated with a decreased vulnerability to early viral infections or chronic inflammatory conditions during preschool years, a reduced incidence of weight excess, and likely lower cholesterol concentration, besides having a small protective effect against systolic blood hypertension.

conclusionsPediatricians must promote breastfeeding, support the mother-infant dyad, and consider breast milk as a real "health voucher" that can last lifelong. However, further studies are needed to better define the extent and duration of breastfeeding's protective power in this context.

Indexed as

Breast FeedingNoncommunicable DiseasesChild, PreschoolFemaleHumansInfantInfant, NewbornMilk, Humanbreastfeedingbreast milknon-communicable diseasesprevention

Identifiers

PMID39940369
PMCPMC11819769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.