Evidence map›Paper›PMID 39940367›Full record

ArticleNutrients2025

Geriatric Nutritional Risk Index (GNRI) and Survival in Pancreatic Cancer: A Retrospective Study.

Christina Grinstead, Saunjoo L Yoon

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christina GrinsteadDepartment of Biobehavioral Nursing Science, College of Nursing, University of Florida, 1225 Center Drive, P.O. Box 100187, Gainesville, FL 32610-0187, USA.ORCID 0000-0002-6165-0635
Saunjoo L YoonDepartment of Biobehavioral Nursing Science, College of Nursing, University of Florida, 1225 Center Drive, P.O. Box 100187, Gainesville, FL 32610-0187, USA.ORCID 0000-0001-5669-8709

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
UF Clinical and Translational Science AwardUL1TR000064 · NCATS · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2012 to 2014
$12.2M
15/24- Healthy Brain and Child Development National ConsortiumU01DA055358 · NIDA · UNIVERSITY OF FLORIDA · PI GURKA, KELLY K., SCOTT, LISA S. · 2021 to 2023
$3.7M
NCATS NIH HHS UL1 TR000064NCATS NIH HHS UL1 TR001427NIDA NIH HHS U01 DA055358
6 · The paper itself

Abstract

introductionMalnutrition is a major contributor to poor treatment and survival outcomes in pancreatic cancer, yet nutritional assessment is not standardized or consistently implemented in the care of oncology patients. The Geriatric Nutritional Risk Index (GNRI), calculated from serum albumin and body weight, may be useful as a practical tool for identifying patients at risk of poor nutritional status.

methodsThis retrospective study included 314 patients aged ≥18 years with pancreatic cancer. The GNRI was calculated at diagnosis and ≥30 days later. Patients were categorized by the GNRI at diagnosis (no risk >98, any risk ≤98) and change in the GNRI over time (no change/increase, mild decrease, and severe decrease). Additional variables included were demographics and stage. Comparative analysis included

resultsMedian survival was significantly decreased in patients in the

conclusionsLower GNRI scores showing greater nutritional risk at diagnosis and decreasing GNRI scores over time were predictors of decreased survival in pancreatic cancer. Our findings indicate that the GNRI may be valid and effective for the early identification of patients with a high nutritional risk who require nutritional interventions to improve outcomes in pancreatic cancer. However, more research is needed using larger samples and a greater variety of variables to confirm the presence and strength of this relationship, examine the effect of patient factors known to be associated with survival and nutrition, and explore potential influential confounders.

Indexed as

Geriatric AssessmentMalnutritionNutritional StatusNutrition AssessmentPancreatic NeoplasmsAgedAged, 80 and overFemaleHumansKaplan-Meier EstimateMaleMiddle AgedProportional Hazards ModelsRetrospective StudiesRisk AssessmentRisk FactorsSerum AlbumincachexiaGeriatric Nutritional Risk Indexnutritional statuspancreatic cancersurvivalweight loss

Identifiers

PMID39940367
PMCPMC11819935

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.