SynthesisNutrients2025
Short- and Long-Term Nutritional Status in Children and Adolescents with Celiac Disease Following a Gluten-Free Diet: A Systematic Review.
Synthesis in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Irregular follow-up is associated with poorer dietary adherence and iron deficiency in children with celiac disease.European journal of pediatrics · 2026Observational
- Laboratory Monitoring of Nutritional Deficiencies in Children Following Restrictive Diets: A Narrative Review and Risk-Based Considerations.Children (Basel, Switzerland) · 2026Review
- Nutritional status in pediatric celiac disease: evaluation at diagnosis and during follow-up.BMC nutrition · 2026Article
- The Role of Nutrition in Pediatric Gastrointestinal Diseases.Nutrients · 2026Article
- Celiac disease and metabolic syndrome: from risk to a preventive opportunity, in the perspective of children's health.Frontiers in nutrition · 2026Review
- Impact of Mediterranean diet-based nutritional intervention on gluten-free diet, nutritional status, and quality of life in a pediatric celiac population: a randomized controlled trial.Frontiers in nutrition · 2026Article
- Celiac Disease as a Model of Intestinal Malnutrition: Mechanisms and Nutritional Management.Nutrients · 2025Review
- A comparative analysis of nutritional status and quality of life in children with celiac disease and their healthy siblings.European journal of pediatrics · 2025Article
- Empowering Gliadin Detection: A Visible-Code Semiquantitative Lateral Flow System for Rapid and Reliable Results.Journal of agricultural and food chemistry · 2025Article
- Gluten-Free Diet Adherence and BMI z-Scores in Pediatric Celiac Disease: Distinguishing Recovery From Excess Weight Gain.Pediatrics international : official journal of the Japan Pediatric SocietyArticle
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesNumerous studies have highlighted the nutritional imbalances that are commonly observed in children and adolescents diagnosed with celiac disease (CD) who follow a gluten-free diet (GFD). However, the development and timeline of these nutritional deficiencies remain unclear. The aim of the present study is to investigate the short-term (≥6 months to <12 months) and long-term (≥12 months) association between adherence to a GFD and nutrient intake as well as micronutrient blood status in children and adolescents aged from 0 to 18 years with CD.
methodsA systematic review was conducted in PubMed and Scopus for observational studies published up to June 2024.
resultsA total of 15 studies (case-control, cross-sectional, and prospective studies) with 2004 children and adolescents were included. Their quality was assessed using the ROBINS-E tool. Despite the lack of high-quality data and the heterogeneity of the methods used in the included studies, the results of the cross-sectional/case-control studies show that, in the short term, children and adolescents with CD consumed excessive amounts of protein and carbohydrates compared to controls. After long-term adherence to a GFD, significant changes in the diets of children and adolescents with CD persisted. Fat intake was higher, while protein intake remained excessive compared to controls. Based on prospective studies, vitamin C and iodine intake improved both in the short and long term after adherence to a GFD. However, most other nutrients either remain inadequate or continue to decline, indicating that it is difficult to meet nutrient requirements despite dietary adjustments.
conclusionsGaps in adherence to dietary recommendations appear to be widespread in children and adolescents with CD, emphasizing the need for improved diet quality and regular monitoring.
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