Evidence map›Paper›PMID 39940316›Full record

ArticleNutrients2025

Effects of Vegetable and Fruit Juicing on Gut and Oral Microbiome Composition.

Maria Luisa Savo Sardaro, Veronika Grote, Jennifer Baik, Marco Atallah, Katherine Ryan Amato, Melinda Ring

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria Luisa Savo SardaroDepartment of Anthropology, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0002-2258-9544
Veronika GroteOsher Center for Integrative Health, Northwestern University, Chicago, IL 60611, USA.
Jennifer BaikDepartment of Anthropology, Northwestern University, Evanston, IL 60208, USA.ORCID 0009-0003-9987-3660
Marco AtallahDepartment of Food Science and Human Nutrition, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0002-7146-4860
Katherine Ryan AmatoDepartment of Anthropology, Northwestern University, Evanston, IL 60208, USA.
Melinda RingOsher Center for Integrative Health, Northwestern University, Chicago, IL 60611, USA.

Funding

Osher Center for Integrative Medicine IM AWARE Advisory Council Research Pilot Grants
6 · The paper itself

Abstract

backgroundIn recent years, juicing has often been promoted as a convenient way to increase fruit and vegetable intake, with juice-only diets marketed for digestive cleansing and overall health improvement. However, juicing removes most insoluble fiber, which may diminish the health benefits of whole fruits and vegetables. Lower fiber intake can alter the microbiota, affecting metabolism, immunity, and mental health, though little is known about juicing's specific effects on the microbiota. This study addresses this gap by exploring how juicing impacts gut and oral microbiome composition in an intervention study.

methodsFourteen participants followed one of three diets-exclusive juice, juice plus food, or plant-based food-for three days. Microbiota samples (stool, saliva, and inner cheek swabs) were collected at baseline, after a pre-intervention elimination diet, immediately after juice intervention, and 14 days after intervention. Moreover, 16S rRNA gene amplicon sequencing was used to analyze microbiota taxonomic composition.

resultsThe saliva microbiome differed significantly in response to the elimination diet (unweighted UniFrac: F = 1.72, R = 0.06,

conclusionsThese findings suggest that short-term juice consumption may negatively affect the microbiota.

Indexed as

DietFruitFruit and Vegetable JuicesGastrointestinal MicrobiomeMicrobiotaMouthVegetablesAdultBacteriaDietary FiberFecesFemaleHumansMaleMiddle AgedRNA, Ribosomal, 16SDietary FiberRNA, Ribosomal, 16Sdiet recommendationsfruit juicinggut microbiomejuice fastsoral microbiome

Identifiers

PMID39940316
PMCPMC11820471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.