Evidence map›Paper›PMID 39940172›Full record

ArticleNanomaterials (Basel, Switzerland)2025

Cuttlefish-Bone-Derived Hybrid Composite Scaffolds for Bone Tissue Engineering.

Vignesh Raj Sivaperumal, Sutha Sadhasivam, Ramalingam Manikandan, Ilanchezhiyan Pugazhendi, Saravanan Sekar, Youngmin Lee, Sejoon Lee, Sankar Sekar

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. International journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vignesh Raj SivaperumalDepartment of Pharmaceutical Technology, Dhanalakshmi Srinivasan Engineering College (Autonomous), Perambalur 621 212, Tamil Nadu, India.
Sutha SadhasivamDepartment of Chemistry, CMS College of Engineering, Ernapuram, Namakkal 637 003, Tamil Nadu, India.
Ramalingam ManikandanDepartment of Analytical Chemistry, University of Madras, Chennai 600 025, Tamil Nadu, India.
Ilanchezhiyan PugazhendiQuantum-Functional Semiconductor Research Center, Dongguk University-Seoul, Seoul 04620, Republic of Korea.
Saravanan SekarDepartment of Mechanical Engineering, K. Ramakrishnan College of Technology, Trichy 621 112, Tamil Nadu, India.
Youngmin LeeQuantum-Functional Semiconductor Research Center, Dongguk University-Seoul, Seoul 04620, Republic of Korea.ORCID 0000-0002-8685-3033
Sejoon LeeQuantum-Functional Semiconductor Research Center, Dongguk University-Seoul, Seoul 04620, Republic of Korea.ORCID 0000-0002-4548-7436
Sankar SekarQuantum-Functional Semiconductor Research Center, Dongguk University-Seoul, Seoul 04620, Republic of Korea.ORCID 0000-0001-9554-2328

Funding

National Research Foundation (NRF) of Korea 2021R1I1A1A01049638 and 2023R1A2C1005421
6 · The paper itself

Abstract

Current investigations into the fabrication of innovative biomaterials that stimulate cartilage development result from increasing interest due to emerging bone defects. In particular, the investigation of biomaterials for musculoskeletal therapies extensively depends on the development of various hydroxyapatite (HA)/sodium alginate (SA) composites. Cuttlefish bone (CFB)-derived composite scaffolds for hard tissue regeneration have been effectively illustrated in this investigation using a hydrothermal technique. In this, the HA was prepared from the CFB source without altering its biological properties. The as-developed HA nanocomposites were investigated through XRD, FTIR, SEM, and EDX analyses to confirm their structural, functional, and morphological orientation. The higher the interfacial density of the HA/SA nanocomposites, the more the hardness of the scaffold increased with the higher applied load. Furthermore, the HA/SA nanocomposite revealed a remarkable antibacterial activity against the bacterial strains such as

Indexed as

biocompatibilitycuttlefish bonehydrothermalhydroxyapatitescaffolds

Identifiers

PMID39940172
PMCPMC11820519

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.