Evidence map›Paper›PMID 39940015›Full record

ArticleJournal of nanobiotechnology2025

Bacterial membrane-modified cerium oxide nanoboosters enhance systemic antitumor effects of radiotherapy in metastatic triple-negative breast cancer.

Shuo-Fu Chen, Pui-Lam Ng, Chen-Wei Lai, Fu-Jia Wang, Yu-Chi Wang, Ming-Hong Chen, Fu-I Tung, Tse-Ying Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shuo-Fu Chen *Department of Heavy Particles & Radiation Oncology, Taipei Veterans General Hospital, Taipei, 112, Taiwan.
Pui-Lam Ng *Department of Biomedical Engineering, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan.
Chen-Wei LaiDepartment of Biomedical Engineering, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan.
Fu-Jia WangDepartment of Biomedical Engineering, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan.
Yu-Chi WangDepartment of Biomedical Engineering, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan.
Ming-Hong ChenDivision of Neurosurgery, Department of Surgery, Far Eastern Memorial Hospital, New Taipei City, 220, Taiwan.
Fu-I TungDepartment of Orthopaedics, Yang-Ming Branch, Taipei City Hospital, Taipei, 111, Taiwan. amsephk@gmail.com.
Tse-Ying LiuDepartment of Biomedical Engineering, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan. tyliu5@nycu.edu.tw.

Funding

Department of Health, Taipei City Government 11201-62-004 and 11301-62-048National Science and Technology Council MOST 111-2221-E-A49-051-MY2, MOST 111-2811-E-A49A-007-MY2, MOST 111-2314-B-038-094
6 · The paper itself

Abstract

backgroundRadiotherapy plays an important role in the treatment of triple-negative breast cancer, yet its ability to trigger systemic responses against distant tumors remains limited.

resultsTo address this challenge, we developed a biomimetic nanobooster by incorporating cerium oxide (CeO

conclusionsIn conclusion, our CeO

Indexed as

Antineoplastic AgentsBacterial Outer MembraneCeriumNanoparticlesTriple Negative Breast NeoplasmsAnimalsCell Line, TumorFemaleHumansMiceMice, Inbred BALB CAntineoplastic Agentsceric oxideCeriumAbscopal effectBacterial outer membrane vesiclesBreast cancerCerium oxideNanoparticlesRadiotherapy

Identifiers

PMID39940015
PMCPMC11823237

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.