Evidence map›Paper›PMID 39939956›Full record

Trial reportBMC anesthesiology2025

Risk and benefit analysis of single-shot nerve block for postoperative analgesia for uniportal video-assisted thoracic surgery (uVATS): a randomized controlled trial.

Li Fang Wang, Fei Qi, Hong Xiang Feng, Yu Hui Shi, Yan Li, Meng Tao Zheng, Tegeleqi Bu, Wei Xia Li, Zhen Rong Zhang

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06016777 (Optimization of Perioperative Analgesia Protocol for Uniportal Video-assisted Thoracoscopic Surgery), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06016777 naunknown statusnot on this map

Optimization of Perioperative Analgesia Protocol for Uniportal Video-assisted Thoracoscopic Surgery: a Randomized Controlled Trial

TypeinterventionalSponsorChina-Japan Friendship HospitalRan2023 to 2025Enrolled102ConditionsUniportal Video-assisted Thoracic SurgeryArmsUltrasound-guided paraspinal block and patient-controlled intravenous analgesia pump, Ultrasound-guided erector spinal block and patient-controlled intravenous analgesia pump, Patient-controlled intravenous analgesia pump
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Li Fang WangDepartment of Anesthesiology, China-Japan Friendship Hospital, Beijing, China.
Fei QiDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Hong Xiang FengDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Yu Hui ShiDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Yan LiDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Meng Tao ZhengDepartment of Anesthesiology, China-Japan Friendship Hospital, Beijing, China.
Tegeleqi BuDepartment of Anesthesiology, Peking University First Hospital, Beijing, China.
Wei Xia LiDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China.
Zhen Rong ZhangDepartment of Thoracic Surgery, China-Japan Friendship Hospital, Beijing, China. doctor_zzr@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is lack of the clinical evidence of optimized perioperative analgesic protocol for uniportal video-assisted thoracoscopic surgery (uVATS).

methodsWe performed a RCT enrolling participants scheduled for uVATS (Trial registration: NCT06016777; registration date: Aug 28, 2023). Participants were randomized for thoracic paravertebral block combined with patient-controlled intravenous analgesia (PVB + PCIA), erector spinae block combined with PCIA (ESPB + PCIA), or PCIA group. Participants were followed-up till 6 months. Primary outcome was total opioid consumption. Secondary outcomes included postoperative rest and cough pain scores, ambulation time, chest tube duration, length of stay, anaesthesia expense and adverse events.

resultsWe enrolled 108 participants between October 16th, 2023 to April 14th, 2024. Neural block did not reduce opioid consumption. Postoperative rest and cough pain scores did not differ among the groups at all the follow-up time points. None of the participants experienced chronic pain. The ambulation time, duration of chest tube maintenance and length of stay did not differ among groups. Duration of anaesthesia procedure was significantly prolonged in both neural blockade groups compared to PCIA group (p = 0.033). Anaesthesia expenses were significantly higher in both nerve block groups than in the PCIA group (p < 0.001). Adverse events related to neural blockade occurred in 17.9% in PVB + PCIA group and 2.9% in ESPB + PCIA group (p = 0.010), including local haemorrhage and block failure. Adverse events related to opioid use did not differ among groups.

conclusionsBoth PVB and ESPB did not exhibit analgesic advantage for uVATS. Neural block may carry the risk of haemorrhage and block failure, prolonged the anaesthesia procedure and increased the anaesthesia expenses.

trial registrationClinical Trial Number was NCT06016777, trial registration date was Aug 28th, 2023.

Indexed as

Nerve BlockPostoperative PainThoracic Surgery, Video-AssistedAdultAgedAnalgesia, Patient-ControlledAnalgesics, OpioidFemaleHumansMaleMiddle AgedRisk AssessmentAnalgesics, OpioidNerve blockPostoperative painSingle-shotThoracic surgeryUniportal

Identifiers

PMID39939956
PMCPMC11816525

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.