ReviewMicrobial cell factories2025
Microbial lipases: advances in production, purification, biochemical characterization, and multifaceted applications in industry and medicine.
Review in Microbial cell factories, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Recombinant thermotolerant alkaline lipase from Lysinibacillus fusiformis for detergent and hard (Ras) cheese applications: cloning, expression, molecular docking, and characterization.Microbial cell factories · 2026Article
- Screening and Fermentation Parameter Optimization of Lipase-ProducingMicroorganisms · 2026Article
- Microbial Enzyme Production: Critical Bottlenecks and Integrated Engineering Solutions.Journal of basic microbiology · 2026Review
- Tailoring ω-3 fatty acid enrichment through genipin, glutaraldehyde, and glyoxyl linked immobilization of Rhizomucor miehei lipase on MWCNTs.World journal of microbiology & biotechnology · 2026Article
- Insect Gut Microbiota as a Reservoir of Industrially Relevant Enzymes: A Comprehensive Review.Microbial ecology · 2026Review
- Development of a Sustainable Biocatalytic Process for Geranyl Benzoate Production Using Immobilized Lipase.ChemistryOpen · 2026Article
- Immobilized Aspergillus niger lipase over hydrogen titanate nanotubes as a biocatalyst for biodiesel production.Biotechnology letters · 2026Article
- Purification and Characterization of an Alkaline Lipase fromACS omega · 2026Article
- Efficient Degradation of Monoacylglycerols by an EngineeredMolecules (Basel, Switzerland) · 2026Article
- Enhancing functional and nutritional properties of wheat-based bakery products using microbial lipases.Food chemistry: X · 2026Review
- Microbiota and lipid mediators: from molecular crosstalk to therapeutic opportunities.Frontiers in pharmacology · 2026Review
- Sulfonamide resistance, virulence traits, and in-silico target interactions among clinical isolates in Setif, Algeria (2021-2023).Iranian journal of microbiology · 2025Article
- Enzymatic biodegradation of used engine oil using a novel lipase derived from renewable feedstocks.World journal of microbiology & biotechnology · 2025Article
- Impact of Ethanol Stress onFoods (Basel, Switzerland) · 2025Article
- Whole genome sequence analysis of a novel3 Biotech · 2025Article
- Biochemical characterization of lipase from Cryptococcus albidus (D24) and its application in sugar fatty acid ester synthesis.Archives of microbiology · 2025Article
- Genetically modified lipases as biocatalysts for diacylglycerol production in the food industry: a critical review.Archives of microbiology · 2025Review
- Versatile biocatalyst: lipase fromFrontiers in bioengineering and biotechnology · 2025Article
- Microbial Enzymes in Industrial Biotechnology: Sources, Production, and Significant Applications of Lipases.Journal of industrial microbiology & biotechnology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lipases are biocatalysts of significant industrial and medical relevance, owing to their ability to hydrolyze lipid substrates and catalyze esterification reactions under mild conditions. This review provides a comprehensive overview of microbial lipases' production, purification, and biochemical properties. It explores optimized fermentation strategies to enhance enzyme yield, including using agro-industrial residues as substrates. The challenges associated with purification techniques such as ultrafiltration, chromatography, and precipitation are discussed, alongside methods to improve enzyme stability and specificity. Additionally, the review addresses the growing importance of genetic engineering approaches for improving lipase characteristics, such as activity, stability, and specificity.Additionally, this review highlights the diverse applications of microbial lipases in industries, including food, pharmaceuticals, biofuels, and cosmetics. The enzyme's role in bioremediation, biodegradation, and the synthesis of bioactive compounds is analyzed, emphasizing its potential in sustainable and eco-friendly technologies. The biocatalytic properties of lipases make them ideal candidates for the green chemistry initiatives in these industries. In the biomedical domain, lipase has shown promise in drug delivery systems, anti-obesity treatments, and diagnostics.This review provides insights into the strategic development of microbes as microbial cell factories for the sustainable production of lipases, paving the way for future research and industrial innovations in enzyme technology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.