Evidence map›Paper›PMID 39939867›Full record

ArticleBiology of sex differences2025

Examining the role of social determinants of health in maternal mental health screening and treatment engagement during the perinatal period.

Leah A Holcomb, Lizmarie Maldonado, Paul J Nietert, Marie A Hayes, Sara M Witcraft, Roger B Newman, Kathleen T Brady, Aimee L McRae-Clark, Kevin M Gray, Constance Guille

Abstract read
In one paragraph

Article in Biology of sex differences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Birth Equity and Maternal Health Among Immigrant Communities in the United States: A Narrative Review.International journal of environmental research and public health · 2026
    Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Leah A HolcombDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA.
Lizmarie MaldonadoDepartment of Healthcare Leadership and Management, Medical University of South Carolina, Charleston, SC, USA.
Paul J NietertDepartment of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA.
Marie A HayesDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA.
Sara M WitcraftDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA.
Roger B NewmanDepartment of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, SC, USA.
Kathleen T BradyDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA.
Aimee L McRae-ClarkDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA.
Kevin M GrayDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA.
Constance GuilleDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA. guille@musc.edu.

Funding

South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
Clinical Scientists Training Program in Addictions at MUSCK12DA031794 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Kevin M. Gray, AIMEE L MCRAE-CLARK · 2013 to 2026
$7.2M
NCATS NIH HHS TR001450NCATS NIH HHS UL1 TR001450NIDA NIH HHS DA016511NIDA NIH HHS DA031794NIDA NIH HHS K12 DA031794
6 · The paper itself

Abstract

backgroundMaternal mental health conditions are associated with unmet Social Determinants of Health (SDOH) needs and can impede access to mental health and substance use disorder (SUD) treatment, leading to poor maternal and newborn health outcomes. A text/phone-based maternal mental health screening and referral to treatment intervention, Listening to Women and Pregnant and Postpartum People (LTWP), has demonstrated improved rates of screening, screening positive for mental health concerns, referral to and attendance of mental health and SUD treatment compared to usual care (i.e., in-person screening and referral). It is unknown, however, if LTWP improves identification of individuals with unmet SDOH needs. This study examines rates of screening, screening positive, referral and attendance to mental health treatment among those with unmet SDOH needs compared to those not experiencing unmet SDOH needs.

methodsThis secondary analysis includes participants randomized to LTWP and endorsing one or more unmet SDOH need (n = 78) or no unmet SDOH need (n = 103) measured by the Accountable Health Communities Health-Related Social Needs Screening Tool via an online survey. Differences in groups' rates of completing a screening, screening positive, being referred to treatment and attending treatment were compared between groups using chi-square tests and relative risk as a measure of association. Adjustments for missing SDOH data via multiple imputations were performed for analysis of the full cohort of LTWP endorsing at least one unmet SDOH need (n = 106) or no unmet SDOH need (n = 118).

resultsAmong LTWP participants, 43.0% (78/181) reported at least one unmet SDOH need with financial strain (55.1% (43/78)), disabilities (34.6% (27/78)), and food insecurity (33.3% (26/78)) being the most frequently reported SDOH. On average, participants with SDOH needs were significantly younger (29.0 vs. 32.0 years), more likely to self-identify as non-Hispanic Black (42.3% vs 13.6%), and report a lower household annual income (33.3% vs 1.9% under $25,000), compared to those without SDOH needs. Those with SDOH needs were more likely to screen positive for mental health concerns (RR: 1.59; 95% CI: 1.21-2.09), be referred to (RR: 2.97; 95% CI: 1.36-6.48), and attend mental health treatment (RR: 2.64; 95% CI 1.04-2.73) compared to those without SDOH needs.

conclusionsThe LTWP intervention, a simple text- and phone-based screening approach with referral to care as needed, shows promise in increasing access to mental health and substance use treatment for individuals with unmet social determinants of health needs and demonstrates potential to enhance screening, identification, and treatment attendance rates for perinatal mental health disorders and substance use disorders compared to traditional in-person systems.

Indexed as

Mental DisordersMental HealthSocial Determinants of HealthAdultFemaleHumansMass ScreeningPerinatal CarePregnancyYoung AdultMental healthPostpartumPregnancySocial determinants of healthSubstance use

Identifiers

PMID39939867
PMCPMC11823023

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.