Evidence map›Paper›PMID 39939841›Full record

ArticleBMC public health2025

Pre-departure PCR testing of travellers for SARS-CoV-2 was an effective tool in limiting transmission in Greenland during the early phases of the COVID-19 pandemic.

Mie Møller, Kasper Sommerlund Moestrup, Trine Abelsen, Peter Vedsted, Kåre Mølbak, Anders Koch

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mie MøllerInstitute of Health and Nature, University of Greenland, Manutooq 1, Nuussuaq, Nuuk, 3905, Greenland. mimoe@uni.gl.
Kasper Sommerlund MoestrupCentre of Excellence for Health, Immunity and Infections (CHIP), Rigshospitalet, Copenhagen, Denmark.
Trine AbelsenThe National Board of Health, Nuuk, Greenland.
Peter VedstedIlulissat Regional Hospital, Ilulissat, Greenland.
Kåre MølbakDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.
Anders KochInstitute of Health and Nature, University of Greenland, Manutooq 1, Nuussuaq, Nuuk, 3905, Greenland.

Funding

Greenland Research Council 80.39Grosserer L. F. Foghts Fond 22.288Læge Sofus Carl Emil Friis og Hustru Olga Doris Friis' Legat FID4401466
6 · The paper itself

Abstract

backgroundDuring the early part of the COVID-19 pandemic, travel restrictions were implemented in Greenland to contain SARS-CoV-2 transmission. Despite their widespread use, empirical evidence supporting the effectiveness of travel restrictions is scarce. Greenland was in a unique position to maintain pre-departure testing among travellers, and we aimed to describe the effectiveness of pre-departure testing to inform the implementation of travel restrictions in future outbreaks.

methodsOur analysis included SARS-Cov-2 PCR test results from travellers, including children, arriving in Greenland from Denmark between June 15, 2020, and January 26, 2022. Additionally, we identified positive tests performed within 14 days post-arrival to Greenland in this population. We estimated the sensitivity of pre-departure screening by dividing the number of positive cases identified pre-departure by the sum of cases identified pre-departure and within 14 days post-arrival in Greenland.

resultsOur analysis covered around 43% of all travellers who underwent pre-departure screening. Out of 26,406 SARS-CoV-2 PCR tests, the proportion of positive tests was 0.6%, which varied over time according to the incidence in Denmark. Overall sensitivity of pre-departure screening was 59% and decreased over time, reaching a minimum of 36% in January 2022. The overall proportion of positive PCR post-arrival tests among all travellers was 0.4%.

conclusionsImplementing pre-departure PCR testing for SARS-CoV-2 among travellers can be effective in the early stages of outbreaks, particularly in geographical regions like Greenland where community transmission had not yet occurred. Our findings suggest that pre-departure screening of travellers contributed to delaying community transmission in Greenland compared to most other countries, thereby reducing the COVID-19 disease burden.

Indexed as

COVID-19COVID-19 Nucleic Acid TestingQuarantineTravelAdultCost of IllnessFemaleGreenlandHumansIncidenceMaleMiddle AgedSARS-CoV-2COVID-19Exit screeningGreenlandSARS-CoV-2 testingTravel measures

Identifiers

PMID39939841
PMCPMC11823211

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.