Evidence map›Paper›PMID 39939809›Full record

ArticleScientific reports2025

Utilizing GPT-4 to interpret oral mucosal disease photographs for structured report generation.

Zheng-Zhe Zhan, Yu-Tao Xiong, Chen-Yuan Wang, Bao-Tian Zhang, Wen-Jun Lian, Yu-Min Zeng, Wei Liu, Wei Tang, Chang Liu

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zheng-Zhe Zhan *State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.ORCID 0009-0008-2659-9943
Yu-Tao Xiong *State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.ORCID 0000-0003-1257-4055
Chen-Yuan WangState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.ORCID 0009-0007-2813-4034
Bao-Tian ZhangState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.
Wen-Jun LianState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.ORCID 0009-0007-4405-6750
Yu-Min ZengState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.ORCID 0009-0004-1257-6135
Wei LiuState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.ORCID 0000-0002-1470-3538
Wei TangState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China. mydrtw@vip.sina.com.ORCID 0000-0001-7568-2884
Chang LiuState Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China. liu_chang_92@sina.com.ORCID 0000-0002-1232-8308

Funding

Research and Develop Program, West China Hospital of Stomatology Sichuan University RD-03-202303Sichuan Science and Technology Program 2024NSFSC0659
6 · The paper itself

Abstract

The aim of this study is to evaluate GPT-4's reasoning ability to interpret oral mucosal disease photos and generate structured reports from free-text inputs, while exploring the role of prompt engineering in enhancing its performance. Prompt received by utilizing automatic prompt engineering and knowledge of oral physicians, was provided to GPT-4 for generating structured reports based on cases of oral mucosal disease. The structured reports included 7 fine-grained items: "location", "shape", "number", "size", "clinical manifestation", "the border of the lesion" and "diagnosis". 120 cases were used for testing, which were divided into two datasets, textbook dataset and internet dataset. Oral physicians evaluated GPT-4's responses by confusion matrices, receiving recall and accuracy. ANOVA and Wald χ2 tests with Bonferroni correction were used to statistical analysis. A total of 120 cases of oral mucosal diseases were included, encompassing the following two datasets: textbook dataset (n = 60), internet dataset (n = 60). GPT-4 had higher recall with the textbook dataset compared to the internet dataset (90.73% vs 89.12%; P = .462, χ

Indexed as

Mouth DiseasesMouth MucosaPhotographyFemaleHumansInternetMaleArtificial intelligenceGPTOral mucosal diseasePhotographsReports

Identifiers

PMID39939809
PMCPMC11821891

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.