ArticleNature2025
Genetic architecture in Greenland is shaped by demography, structure and selection.
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In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Contrasting ancestry patterns inferred from Y chromosome and mitochondrial DNA in Nanjing people from southwestern China.Human genetics · 2026Article
- Brown Adipose Tissue and Metabolic Markers Differ Between Greenlanders and Danes With Cold Activation.The Journal of clinical endocrinology and metabolism · 2026Article
- Genetic determinants of plasma lipids in Greenlanders.Current opinion in lipidology · 2026Review
- Article
- Genetic regulation of the plasma proteome and its link to cardiometabolic disease in Greenlandic Inuit.American journal of human genetics · 2025Article
- Heterogeneity in the development of diabetes-related complications: narrative review of the roles of ancestry and geographical determinants.Diabetologia · 2025Review
- Societal and biological approaches to diabetes prevention and care for Inuit populations: a narrative review.Diabetologia · 2025Review
- Polygenic risk score for type 2 diabetes shows context-dependent effects across populations.Nature communications · 2025Article
- Comparative assessment of the Sikun 2000 sequencing platform for whole genome sequencing.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors.
Frederik Filip StægerDepartment of Biology, Section for Computational and RNA Biology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-2295-8637
Mette K AndersenNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-8227-1469
Zilong LiDepartment of Biology, Section for Computational and RNA Biology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-5859-2078
Jasmin Pernille HjerresenNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0009-0009-5613-8096
Shixu HeDepartment of Biology, Section for Computational and RNA Biology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-8890-0844
Cindy G SantanderDepartment of Biology, Section for Computational and RNA Biology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-3021-6809
Rasmus Tanderup JensenNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Karsten Fleischer RexDepartment of Internal Medicine, Queen Ingrid's Hospital, Nuuk, Greenland.
Anne Cathrine Baun ThuesenNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Kristian HanghøjDepartment of Biology, Section for Computational and RNA Biology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-1941-5495
Inge Høst SeidingIlisimatusarfik - University of Greenland, Nuuk, Greenland.
Emil JørsboeNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-0593-7906
Sara Elizabeth StinsonNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-1491-9179
Malthe Sebro RasmussenDepartment of Biology, Section for Computational and RNA Biology, University of Copenhagen, Copenhagen, Denmark.
Renzo F BalboaDepartment of Biology, Section for Computational and RNA Biology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-2821-8020
Christina Viskum Lytken LarsenCentre for Public Health in Greenland, National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
Peter BjerregaardCentre for Public Health in Greenland, National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
Mikkel SchubertNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Jonas MeisnerNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-9540-6673
Allan LinnebergCenter for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark, Copenhagen, Denmark.ORCID 0000-0002-0994-0184
Niels GrarupNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-5526-1070
Eleftheria ZegginiInstitute of Translational Genomics, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
Rasmus NielsenDepartments of Integrative Biology and Statistics, University of California at Berkeley, California, CA, USA.ORCID 0000-0003-0513-6591
Marit E JørgensenCentre for Public Health in Greenland, National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.ORCID 0000-0001-8356-5565
Torben HansenNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. torben.hansen@sund.ku.dk.ORCID 0000-0001-8748-3831
Ida MoltkeDepartment of Biology, Section for Computational and RNA Biology, University of Copenhagen, Copenhagen, Denmark. ida@bio.ku.dk.ORCID 0000-0001-7052-8554
Anders AlbrechtsenDepartment of Biology, Section for Computational and RNA Biology, University of Copenhagen, Copenhagen, Denmark. aalbrechtsen@bio.ku.dk.ORCID 0000-0001-7306-031X
Funding
Enabling Precision Genomics Using Adaptive VariationR01GM138634 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI NIELSEN, RASMUS · 2020 to 2023
$1.7MInference and application of graphs for genomic dataR35GM153400 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI RASMUS NIELSEN · 2024 to 2026
$1.3MNIGMS NIH HHS R01 GM138634NIGMS NIH HHS R35 GM153400Novo Nordisk Foundation
Abstract
Greenlandic Inuit and other indigenous populations are underrepresented in genetic research
Indexed as
DemographyGenome, HumanInuitSelection, GeneticArctic RegionsEuropeFemaleGenetic DriftGenome-Wide Association StudyGreenlandHumansMaleMultifactorial InheritancePhenotypeWhiteWhite People
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.