ArticleAbdominal radiology (New York)2025
The effect of different adipose tissue measurements on clinical prognosis in bladder cancer patients undergoing radical cystectomy: preliminary results.
Article in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeObesity has been linked to an increased incidence of various cancers, including bladder cancer. Among the different types of adipose tissue, visceral fat is recognized as the most metabolically active. However, there is a notable scarcity of studies investigating the impact of fat distribution, as measured by computed tomography (CT), on the prognosis of bladder cancer patients undergoing radical cystectomy (RC). MATERIALS AND
methodsBetween January 2013 and January 2024, preoperative CT images of 34 patients who underwent RC were analyzed to measure total perivesical fat area (TPFA, mm²), fat density (FD, %), and subcutaneous fat thickness (SFT, mm). Multivariate Cox regression analysis was used to assess the effects of these variables on prognosis.
resultsThe median age (IQR) of the patients was 65.5 years (12.5), and the median BMI (IQR) was 26.05 (5.98) kg/m². The median follow-up period (IQR) was 11 (31.2) months. A positive correlation was observed between BMI, TPFA, and SFT (r = 0.39, p = 0.02; r = 0.69, p < 0.001, respectively). According to Cox regression analysis, SFT, T stage, and N stage were found to be predictive factors for progression (HR = 1.11, p = 0.007; HR = 4.01, p = 0.04; HR = 6.47, p = 0.02, respectively), and T stage was also identified as an independent predictor for overall survival (HR = 5.32, p = 0.04).
conclusionSFT measurement alongside clinical staging would be beneficial in determining progression following RC. Future randomized controlled trials supporting our findings will highlight the significance of these measurements.
Indexed as
Identifiers
39939543What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.