Evidence map›Paper›PMID 39939534›Full record

ArticleThe Journal of membrane biology2025

Schisandrin B Improves Mitochondrial Function and Inhibits HT22 Cell Apoptosis by Regulating Sirt3 Protein.

Fei Hu, Songlin Tong, Hongming Xu

Abstract read
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In one paragraph

Article in The Journal of membrane biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fei HuCixi Biomedical Research Institute, Wenzhou Medical University, Cixi, Ningbo, China.ORCID 0000-0002-1771-8786
Songlin TongDepartment of Orthopaedic Surgery, Affiliated Cixi Hospital, Wenzhou Medical University, No. 999, South Second Ring Road, Hushan Street, Cixi, Ningbo, China.
Hongming XuDepartment of Orthopaedic Surgery, Affiliated Cixi Hospital, Wenzhou Medical University, No. 999, South Second Ring Road, Hushan Street, Cixi, Ningbo, China. 104497554@qq.com.ORCID 0000-0001-7588-8356

Funding

Natural Science Foundation of Ningbo Municipality 2021J031Natural Science Foundation of Ningbo Municipality 2022J049
6 · The paper itself

Abstract

Neurological diseases refer to pathological changes that occur in the brain, spinal cord, and peripheral nerves. Their etiologies are complex, treatment outcomes are poor, and prognoses are unfavorable. Therefore, how to improve the treatment efficacy of neurological diseases is an urgent problem to be addressed in current clinical practice. Schisandrin B, a commonly used traditional Chinese medicine in clinical settings, has anti-tumor, anti-inflammatory, and wound-healing promoting effects. However, there are relatively few studies on its application in the treatment of neurological diseases. In this study, HT22 nerve cells were cultured, and an injury model was constructed by applying H

Indexed as

ApoptosisLignansMitochondriaPolycyclic CompoundsSirtuin 3AnimalsCell LineCell MovementCell SurvivalCyclooctanesEnergy MetabolismHydrogen PeroxideMembrane Potential, MitochondrialMiceNeuronsCyclooctanesHydrogen PeroxideLignansPolycyclic Compoundsschizandrin BSirt3 protein, mouseSirtuin 3ApoptosisInhibitsMitochondrial functionNervous systemSchisandrin B

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.