Evidence map›Paper›PMID 39939529›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2026

Association between potassium fluctuation and in-hospital mortality in acute myocardial infarction patients: a retrospective analysis of the MIMIC-IV database.

Ying Zhou, Yang Chen, Shangyan Liang, Yanling Li, Changlin Zhao, Zhen Wu

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Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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4 citing papers in PubMed.

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6 authors.

Ying Zhou *Department of VIP Medical Service Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.ORCID http://orcid.org/0009-0000-8838-0463
Yang Chen *Department of Cardiology, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, Guangdong, China.
Shangyan LiangDepartment of VIP Medical Service Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Yanling LiDepartment of Emergency, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Changlin ZhaoDepartment of Cardiology, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, Guangdong, China. zhaoclzssy@126.com.
Zhen WuDepartment of Cardiology, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, Guangdong, China. wuzh@mail.sysu.edu.cn.

Funding

Guangdong Province Natural Science Foundation of China 2020A1515010362
6 · The paper itself

Abstract

backgroundSerum potassium levels are recognized for their prognostic significance in patients presenting with acute myocardial infarction (AMI). However, the correlation between potassium level fluctuations and mortality rates among AMI patients remains unclear.

methodsA retrospective cohort study was conducted using the MIMIC-IV database, including deidentified data from patients admitted to the Beth Israel Deaconess Medical Center from 2008 to 2022. Potassium fluctuation was assessed using parameters including mean postadmission serum potassium levels (K

resultsA J-shaped correlation between serum potassium levels and the risk of in-hospital mortality was identified. Both high and low potassium levels were significantly associated with increased mortality. Specifically, K

conclusionsSerum potassium fluctuation is an independent predictive factor for in-hospital mortality among AMI patients. These findings underscore the importance of maintaining potassium homeostasis in the management of AMI, suggesting that monitoring and stabilizing potassium levels are crucial for reducing in-hospital mortality.

Indexed as

Myocardial InfarctionPotassiumAgedBiomarkersDatabases, FactualFemaleHospital MortalityHumansIsraelMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsBiomarkersPotassiumAcute myocardial infarctionIn-hospital mortalityMIMIC-IV databasePotassium fluctuationSerum potassiumVentricular arrhythmias

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.