Evidence map›Paper›PMID 39939483›Full record

ReviewCurrent obesity reports2025

Circadian Disruption and the Risk of Developing Obesity.

Hélène Duez, Bart Staels

Registry-linked trialAbstract readReview
In one paragraph

Review in Current obesity reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07163455 (Time-Restricted Eating), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07163455 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

Time-Restricted Eating (10-Hour Window) for Weight-Loss Maintenance in Adults With Recent Intentional Weight Loss: A Multicenter, 12-Month Randomized Controlled Trial

TypeinterventionalSponsorHarbin Medical UniversityRan2026 to 2028Enrolled500ConditionsOverweight or Obese AdultsArmsScheduled Weight Maintenance Nutrition Education, Time-Restricted Eating (10-Hour Window)
3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Proanthocyanidin-Rich Cranberry Extract Lowers Glycemia in Established Obesity by Delaying Glucose Absorption.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  4. Article
  5. Article
  6. Time of day of induction impacts the total duration of labor.American journal of obstetrics & gynecology MFM · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Sleep habits in the pathogenesis and management of diabesity.Journal of diabetes investigation · 2025
    Review
  13. Chrononutrition: Potential, Challenges, and Application in Managing Obesity.International journal of molecular sciences · 2025
    Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hélène DuezUniv. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000, Lille, France. Helene.duez@pasteur-lille.fr.
Bart StaelsUniv. Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000, Lille, France. bart.staels@pasteur-lille.fr.

Funding

Agence Nationale de la Recherche ANR-10-LABX-0046Agence Nationale de la Recherche ANR-19-CE15-0033-01Fondation pour la Recherche Médicale EQU202003010310Fondation pour la Recherche Médicale EQU202203014650
6 · The paper itself

Abstract

purpose of the reviewThis review summarizes recent evidence for a role of the clock in adipose tissue physiology and the impact of circadian desynchrony on the development of obesity. RECENT

findingsCircadian disruptions due to shift work, late time eating and nighttime light exposure are associated with obesity and its metabolic and cardiovascular consequences. Studies in mice harboring tissue-specific gain/loss of function mutations in clock genes revealed that the circadian clock acts on multiple pathways to control adipogenesis, lipogenesis/lipolysis and thermogenesis. Time-restricted eating (TRE), aligning feeding with the active period to restore clock function, represents a promising strategy to curb obesity. While TRE has shown clear benefits, especially in participants at higher cardiometabolic risk, current studies are limited in size and duration. Larger, well-controlled studies are warranted to conclusively assess the effects of TRE in relation to the metabolic status and gender. Field studies in shift-workers, comparing permanent night shift versus rotating shifts, are also necessary to identify the optimal time window for TRE.

Indexed as

Circadian ClocksCircadian RhythmObesityAdipogenesisAdipose TissueAnimalsHumansMiceRisk FactorsShift Work ScheduleThermogenesisCircadian misalignmentObesityShift-workSocial jetlagTime-restricted eating/feeding

Identifiers

PMID39939483
PMCPMC11821678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.