Evidence map›Paper›PMID 39939458›Full record

ArticleLa Radiologia medica2025

Automation bias in AI-assisted detection of cerebral aneurysms on time-of-flight MR angiography.

Su Hwan Kim, Severin Schramm, Evamaria Olga Riedel, Lena Schmitzer, Enrike Rosenkranz, Olivia Kertels, Jannis Bodden, Karolin Paprottka, Dominik Sepp, Martin Renz and 7 more

Abstract read
In one paragraph

Article in La Radiologia medica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  7. Patient and physician perspectives on large language model generated responses about brain aneurysm.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
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  9. Review
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  11. Evaluation of Approved AI-based Brain Aneurysm Detection Software in Clinical Practice: Comparison with Radiologist Assessment and Image Re-review.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Su Hwan KimInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany. suhwan.kim@tum.de.ORCID http://orcid.org/0000-0002-5383-2041
Severin SchrammInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Evamaria Olga RiedelInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Lena SchmitzerInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Enrike RosenkranzInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Olivia KertelsInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Jannis BoddenInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Karolin PaprottkaInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Dominik SeppInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Martin RenzInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Jan KirschkeInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Thomas BaumInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Christian MaegerleinInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Tobias Boeckh-BehrensInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Claus ZimmerInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Benedikt WiestlerInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Dennis M HedderichInstitute of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine how automation bias (inclination of humans to overly trust-automated decision-making systems) can affect radiologists when interpreting AI-detected cerebral aneurysm findings in time-of-flight magnetic resonance angiography (TOF-MRA) studies. MATERIAL AND

methodsNine radiologists with varying levels of experience evaluated twenty TOF-MRA examinations for the presence of cerebral aneurysms. Every case was evaluated with and without assistance by the AI software © mdbrain, with a washout period of at least four weeks in-between. Half of the cases included at least one false-positive AI finding. Aneurysm ratings, follow-up recommendations, and reading times were assessed using the Wilcoxon signed-rank test.

resultsFalse-positive AI results led to significantly higher suspicion of aneurysm findings (p = 0.01). Inexperienced readers further recommended significantly more intense follow-up examinations when presented with false-positive AI findings (p = 0.005). Reading times were significantly shorter with AI assistance in inexperienced (164.1 vs 228.2 s; p < 0.001), moderately experienced (126.2 vs 156.5 s; p < 0.009), and very experienced (117.9 vs 153.5 s; p < 0.001) readers alike.

conclusionOur results demonstrate the susceptibility of radiology readers to automation bias in detecting cerebral aneurysms in TOF-MRA studies when encountering false-positive AI findings. While AI systems for cerebral aneurysm detection can provide benefits, challenges in human-AI interaction need to be mitigated to ensure safe and effective adoption.

Indexed as

Artificial IntelligenceImage Interpretation, Computer-AssistedIntracranial AneurysmMagnetic Resonance AngiographyAdultAgedAutomationBiasFalse Positive ReactionsFemaleHumansMaleMiddle AgedArtificial intelligenceAutomation biasCerebral aneurysmMR angiography

Identifiers

PMID39939458
PMCPMC12008054

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.