ArticleCurrent biology : CB2025
Transformations in prefrontal ensemble activity underlying rapid threat avoidance learning.
Article in Current biology : CB, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- High-fat diet exposure, internal state, and reward value influence decision making during motivational conflict.Neurobiology of stress · 2026Article
- A shared ensemble in the prelimbic cortex links impulsivity and anxiety-like behavior.bioRxiv : the preprint server for biology · 2025Article
- Dopaminergic projections to the prefrontal cortex are critical for rapid threat avoidance learning.Current biology : CB · 2025Article
- Directed cell-type recruitment during consolidation of a remote memory.bioRxiv : the preprint server for biology · 2025Article
- Modifying the platform-mediated avoidance task: A new protocol to study active avoidance within a social context in rats.PloS one · 2025Article
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6 authors.
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Abstract
To survive, animals must rapidly learn to avoid aversive outcomes by predicting threats and taking preemptive actions to avoid them. Often, this involves identifying locations that are safe in the context of specific, impending threats and remaining in those locations until the threat passes. Thus, animals quickly learn how threat-predicting cues alter the implications of entering or leaving a safe location. The prelimbic subregion (PL) of the medial prefrontal cortex (mPFC) integrates learned associations to influence threat avoidance strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.