Evidence map›Paper›PMID 39937476›Full record

ArticleJAMA network open2025

Electronic Nicotine Delivery System Advertisement Trends After US Federal Policy Changes.

Rui Shi, Amal Khayat, Juhan Lee, Kathleen A Garrison, Rime Jebai, Olivia A Wackowski, Jenny E Ozga, Cassandra A Stanton

Abstract read
In one paragraph

Article in JAMA network open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rui ShiDepartment of Communication Studies, Ric Edelman College of Communication & Creative Arts, Rowan University, Glassboro, New Jersey.
Amal KhayatBraun School of Public Health and Community Medicine, Hadassah Medical Organization, Hebrew University of Jerusalem, Jerusalem, Israel.
Juhan LeeDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, New York.
Kathleen A GarrisonDepartment of Psychiatry, Yale School of Medicine, New Haven, Connecticut.
Rime JebaiDepartment of Health Law, Policy & Management, School of Public Health, Boston University, Boston, Massachusetts.
Olivia A WackowskiInstitute for Nicotine and Tobacco Studies, Rutgers University, Brunswick, New Jersey.
Jenny E OzgaBehavioral Health & Health Policy, Westat, Rockville, Maryland.
Cassandra A StantonBehavioral Health & Health Policy, Westat, Rockville, Maryland.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Center for the Study of Tobacco Product Use and Addiction (YCSTP) Project 2: Addictive Threshold of Nicotine and the Impact of SweetenersU54DA036151 · NIDA · YALE UNIVERSITY · PI SUCHITRA KRISHNAN-SARIN, STEPHANIE S O'MALLEY · 2018 to 2026
$41.6M
Leadership and Logistics CoreU54DA046060 · NIDA · WESTAT, INC. · PI Andrea M Stroup · 2018 to 2026
$28.1M
The impact of e-cigarette advertising and warning labels on e-cigarette use behavior in adolescentsR01DA046334 · NIDA · YALE UNIVERSITY · PI GARRISON, KATHLEEN A. · 2019 to 2021
$1.3M
NCATS NIH HHS UL1 TR001863NIDA NIH HHS R01 DA046334NIDA NIH HHS U54 DA036151NIDA NIH HHS U54 DA046060
6 · The paper itself

Abstract

Importance: The US has implemented several regulatory measures to govern the sale and marketing of electronic nicotine delivery systems (ENDS). A nicotine warning statement requirement became effective in September 2018, the minimum legal age for tobacco and nicotine sales was raised to 21 years (Tobacco to 21 Act [T21]) in December 2019, and a January 2020 enforcement policy limited the sale of cartridge-based ENDS to only tobacco and menthol flavors. Objective: To track the presence of the nicotine warning statement, youth appeals, and flavor cues in the advertisements of 3 ENDS brands with marketing authorization during the implementation of the US federal tobacco policies. Design, Setting, and Participants: In this qualitative study, a content analysis was conducted on ENDS advertisements in the market from November 18, 2015, to June 26, 2022. All mobile, online display, outdoor, and print advertisements from the 3 US ENDS brands with marketing granted orders as of June 2022 were collected through Vivvix, a commercial advertisement intelligence company. Advertisements were excluded if they targeted businesses rather than consumers, contained display errors that were unretrievable, or were duplicates. Data analysis was completed in March 2024. Exposure: The nicotine warning statement requirement, T21, and the flavor enforcement policy. Main Outcomes and Measures: Nicotine warning statement compliance and presence of youth-appealing features (eg, young models, sports, and sex appeal) and nonmenthol, nontobacco flavor cues (eg, images of food, characterizing words like sweet or fruity) in ENDS advertisements before and after policy implementation. Results: Of the 614 advertisements analyzed, the proportion containing the nicotine warning statement increased from 18 of 83 (21.7%) in the year preceding policy implementation to 147 of 152 (96.7%) in the subsequent year (χ21 = 144.5; P < .001). The proportion of advertisements containing any youth-appealing features increased from 35 of 171 (20.5%) in the year before T21 to 64 of 143 (44.8%) in the year after T21 (χ21 = 21.28; P < .001). There was no significant difference in flavor cues in the advertisements in the year before the flavor enforcement policy (30 of 161 [18.6%]) and those in the following year (38 of 149 [25.5%]) (χ21 = 2.13; P = .14). Conclusions and Relevance: This qualitative study found immediate compliance with nicotine warning statements but no significant reduction in use of flavor cues and an increase in youth-appealing features in the first year after regulatory measures. The findings suggest a need for continued close monitoring of youth appeals in ENDS advertisements on all platforms to inform potential policies and interventions that can be used to counter the reach, appeal, and impact of these advertisements.

Indexed as

AdvertisingElectronic Nicotine Delivery SystemsHumansQualitative ResearchUnited States

Identifiers

PMID39937476
PMCPMC11822544

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.