Evidence map›Paper›PMID 39937379›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2025

Chitosan nanoparticles encapsulating farnesol show potent antifungal activity against Candida albicans biofilms.

Adelaide Fernandes Costa, Jacqueline Teixeira da Silva, Juliana Assis Martins, Viviane Lopes Rocha, Andre Correa Amaral

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Decrease of AFMBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  3. The effects of tyrosol on yeasts: an overview of current knowledge.Applied microbiology and biotechnology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adelaide Fernandes CostaBiological Sciences Institute, Universidade Federal de Goiás, Goiânia, GO, Brazil. adelaidefernandes@ufg.br.ORCID https://orcid.org/0000-0002-7947-7236
Jacqueline Teixeira da SilvaInstitute of Tropical Pathology and Public Health, Universidade Federal de Goiás, Goiânia, GO, Brazil.ORCID http://orcid.org/0000-0002-5152-0597
Juliana Assis MartinsInstitute of Tropical Pathology and Public Health, Universidade Federal de Goiás, Goiânia, GO, Brazil.ORCID http://orcid.org/0000-0003-4092-899X
Viviane Lopes RochaInstitute of Tropical Pathology and Public Health, Universidade Federal de Goiás, Goiânia, GO, Brazil.ORCID https://orcid.org/0000-0002-2495-7750
Andre Correa AmaralInstitute of Tropical Pathology and Public Health, Universidade Federal de Goiás, Goiânia, GO, Brazil.ORCID http://orcid.org/0000-0001-9516-8970

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Candida albicans biofilms are characterized as the main virulence factor responsible for therapeutic failure with antifungals and the development of resistant strains. Chitosan nanoparticles with farnesol (NF) may be able to penetrate biofilms due to their small size and enable the delivery of molecules to specific locations. The objective of the study was to assess the in vitro effectiveness of NF on C. albicans biofilms, as an additional study of the previously presented in vivo data. In the antifungal tests with C. albicans ATCC 10231, NF showed an IC

Indexed as

Antifungal AgentsBiofilmsCandida albicansChitosanFarnesolNanoparticlesCandidiasisDrug CarriersMicrobial Sensitivity TestsAntifungal AgentsChitosanDrug CarriersFarnesolAntifungal therapyMicrobial biotechnologyNanotechnologyQuorum sensing

Identifiers

PMID39937379
PMCPMC12095726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.