Evidence map›Paper›PMID 39937331›Full record

ArticleMolecular biology reports2025

Mechanism of Ca

Ziyu Li, Yongkai Yu, Xuechen Cao, Yidan Wang, Jiawei Lu, Yifei Feng, Yali Jiang, Yan Lu

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ziyu LiDepartment of Dermatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Yongkai YuDepartment of Dermatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Xuechen CaoDepartment of Dermatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Yidan WangDepartment of Dermatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Jiawei LuDepartment of Dermatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Yifei FengDepartment of Dermatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Yali JiangThe Friendship Hospital of Ili Kazakh Autonomous Prefecture, Xinjiang Uygur Autonomous Region, Xinjiang, 835000, China. yalijiang@njmu.edu.cn.
Yan LuDepartment of Dermatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. luyan6289@163.com.

Funding

the National Natural Science Foundation of China 82273549the Natural Science Foundation of Jiangsu Province, China BK20221414the Research Fund Project of the Research Institute of Yili Prefecture Clinical Medical College yl2022zd01
6 · The paper itself

Abstract

backgroundVitiligo is a common depigmentation disorder. Oxidative stress in melanocytes is thought to be the primary cause of vitiligo. Imbalances in cellular calcium ion (Ca METHODS AND

resultsSingle-cell RNA sequencing data from vitiligo patients were analyzed using bioinformatics techniques. NHMs were treated with hydrogen peroxide (H

conclusionsOxidative stress upregulates STIM1/ORAI1 expression, leading to melanocyte apoptosis via increased Ca

Indexed as

CalciumMelanocytesMitochondriaNeoplasm ProteinsORAI1 ProteinStromal Interaction Molecule 1ApoptosisCalcium SignalingCells, CulturedHumansHydrogen PeroxideIndolesMembrane Potential, MitochondrialOxidative StressReactive Oxygen SpeciesVitiligoCalciumcyclopiazonic acidHydrogen PeroxideIndolesNeoplasm ProteinsORAI1 ProteinORAI1 protein, humanReactive Oxygen SpeciesSTIM1 protein, humanStromal Interaction Molecule 1ApoptosisCalcium ionORAI1Oxidative stressSOCESTIM1

Identifiers

PMID39937331

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.