Evidence map›Paper›PMID 39937261›Full record

ArticlePain medicine (Malden, Mass.)2025

Clinical and mental health characteristics among patients receiving medications for opioid use disorder treatment versus patients receiving low- and high-dose opioids when referred for pain management.

Jie Yang, Melita Giummarra, Louisa Picco, Carolyn Arnold, Suzanne Nielsen

Abstract read
In one paragraph

Article in Pain medicine (Malden, Mass.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jie YangMonash Addiction Research Centre, Eastern Health Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria 3199, Australia.ORCID 0000-0001-9547-7298
Melita GiummarraCaulfield Pain Management and Research Centre, Caulfield Hospital, Melbourne, Victoria 3162, Australia.ORCID 0000-0001-7839-6058
Louisa PiccoMonash Addiction Research Centre, Eastern Health Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria 3199, Australia.ORCID 0000-0001-7593-3209
Carolyn ArnoldCaulfield Pain Management and Research Centre, Caulfield Hospital, Melbourne, Victoria 3162, Australia.
Suzanne NielsenMonash Addiction Research Centre, Eastern Health Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria 3199, Australia.

Funding

Australian National Health and Medical Research Council #2016909China Scholarship Council #202108440067NHMRC L2, #2025894
6 · The paper itself

Abstract

objectiveTo examine the demographic and clinical characteristics of patients attending pain management services who were receiving opioid agonist treatment (ie, methadone or buprenorphine for the treatment of opioid use disorder) in comparison with those taking prescription opioid analgesics in oral morphine equivalent daily doses at low (<40 mg) and high doses (>100 mg) in a national database from the electronic Persistent Pain Outcomes Collaboration (ePPOC) in Australia.

designA cross-sectional study.

settingAustralian pain services. SUBJECTS: Adult patients referred to Australian pain service clinics between 2016 and 2021.

methodsMultinomial and bivariate logistic regression models were conducted to compare the demographic and clinical characteristics of patients on opioid agonist treatment and those taking other prescription opioid analgesics.

resultsAmong 42 182 participants, most were female (56.8%), with a mean age of 51.7 years. People on opioid agonist treatment (n = 1016) and high-dose opioids (n = 7122) were similar in that they both had more severe mental health symptoms and longer pain duration than the low-dose group (n = 20 517). Compared with the high-dose group, people on opioid agonist treatment had reduced odds of reporting more severe pain intensity but increased odds of having multimorbidity, more severe anxiety, and pain catastrophizing thoughts.

conclusionsThese findings highlight the need for mental health treatment and the necessity of tailored multidisciplinary pain management for people in opioid agonist treatment.

Indexed as

Analgesics, OpioidOpioid-Related DisordersPain ManagementAdultAustraliaBuprenorphineCross-Sectional StudiesFemaleHumansMaleMental HealthMethadoneMiddle AgedOpiate Substitution TreatmentAnalgesics, OpioidBuprenorphineMethadoneAustraliaopioid agonist treatmentopioidspain management

Identifiers

PMID39937261
PMCPMC12046219

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.