Evidence map›Paper›PMID 39937241›Full record

Trial reportSurgical endoscopy2025

Preoperative visceral fat area predicts intraoperative adverse events during lymphadenectomy in laparoscopic gastrectomy for gastric cancer: a post hoc analysis.

Ling-Hua Wei, Hua-Long Zheng, Zhi-Yu Liu, Xiao-Qiang Du, Chun-Sen Chen, Bin-Bin Xu, Hong-Hong Zheng, Guang-Tan Lin, Jian-Wei Xie, Chao-Hui Zheng and 3 more

2 registry-linked trialsAbstract readRandomized Controlled TrialClinical Trial, Phase III
PubMed Publisher
In one paragraph

Trial report in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01609309 phase3unknown statusnot on this map

Multicenter Study on Comparison of Long-term Outcome Between Laparoscopic and Open Distal Subtotal Gastrectomy With D2 Lymphadenectomy for Locally Advanced Gastric Cancer

TypeinterventionalSponsorNanfang Hospital, Southern Medical UniversityRan2012 to 2017Enrolled1,056ConditionsStomach NeoplasmsArmsLaparoscopic gastrectomy, Open gastrectomy
NCT02327481 nacompletednot on this map

Randomized Controlled Trials Comparing Clinical Outcomes of 3D Versus 2D Laparoscopic Surgery for Gastric Cancer

TypeinterventionalSponsorFujian Medical UniversityRan2015 to 2021Enrolled438ConditionsStomach NeoplasmsArms3D Laparoscopic Surgery, 2D Laparoscopic Surgery
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ling-Hua Wei *Department of Gastric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, 350001, China.
Hua-Long Zheng *Department of Gastric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, 350001, China.
Zhi-Yu Liu *Department of Gastric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, 350001, China.
Xiao-Qiang Du *Department of Radiology, Fujian Medical University Union Hospital, Fuzhou, 350001, China.
Chun-Sen ChenDepartment of Radiology, Fujian Medical University Union Hospital, Fuzhou, 350001, China.
Bin-Bin XuDepartment of Gastric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, 350001, China.
Hong-Hong ZhengDepartment of Gastric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, 350001, China.
Guang-Tan LinDepartment of Gastric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, 350001, China.
Jian-Wei XieDepartment of Gastric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, 350001, China.
Chao-Hui ZhengDepartment of Gastric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, 350001, China.
Jia-Bin WangDepartment of Gastric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, 350001, China. 847044493@qq.com.
Chang-Ming HuangDepartment of Gastric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, 350001, China. hcmlr2002@163.com.ORCID 0000-0002-0019-885X
Ping LiDepartment of Gastric Surgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Fuzhou, 350001, China. pingli811002@163.com.ORCID 0000-0002-9418-9339

Funding

Fujian Provincial Health Technology Project 2022QNA026Fujian Research and Training Grants for Young and Middle-aged Leaders in Healthcare No.[2022]954
6 · The paper itself

Abstract

backgroundVisceral obesity has been increasingly recognized as a potential risk factor for surgical complications in gastric cancer surgery, yet its impact on lymphadenectomy during laparoscopic gastrectomy remains undefined. This study aimed to investigate the influence of visceral fat area (VFA) on intraoperative adverse events (iAEs) during lymphadenectomy in laparoscopic gastrectomy.

methodsA post hoc analysis was performed using data from two previous prospective studies ([NCT02327481] and [NCT01609309]). The patients were divided into high and low VFA groups based on preoperative computed tomography images at the umbilical level. All iAEs were reviewed from the surgical videos and graded using ClassIntra. The factors influencing iAEs were identified, and predictive models for iAEs were constructed.

resultsThis study included 490 patients, with 244 and 246 patients in the high and low VFA groups, respectively. Restricted cubic splines demonstrated a positive linear association between VFA and iAEs. Compared with the low VFA group, the high VFA group exhibited a significantly higher incidence of iAEs (29% vs. 12%, p < 0.001), primarily in the infrapyloric (9.0% vs. 2.0%) and suprapancreatic (23.4% vs. 9.3%) regions and higher rates of ClassIntra I-III. Multivariate logistic regression identified high VFA as an independent risk factor for iAEs (hazard ratio [HR] 2.16, 95% confidence interval [CI]: 1.22 - 3.83). Based on the VFA, nomograms were developed to predict iAEs (training area under the curve [AUC] 0.722, validation AUC 0.730). Meanwhile, a web-based calculator was developed to facilitate clinical application.

conclusionsHigh preoperative VFA is independently correlated with iAEs after laparoscopic gastrectomy for gastric cancer. Nomograms based on VFA showed potential in predicting iAEs, helping identify high-risk patients early and facilitating tailored perioperative management.

Indexed as

GastrectomyIntra-Abdominal FatIntraoperative ComplicationsLaparoscopyLymph Node ExcisionObesity, AbdominalStomach NeoplasmsAgedFemaleHumansMaleMiddle AgedPreoperative PeriodProspective StudiesRisk FactorsTomography, X-Ray ComputedGastric cancerIntraoperative adverse eventsLaparoscopic surgeryVisceral fat area

Identifiers

PMID39937241

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.