Evidence map›Paper›PMID 39937191›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

Long-term follow-up of non‑neurologic and neurologic complications after complex adult spinal deformity surgery: results from the Scoli-RISK-1 study.

Meghan Cerpa, Scott L Zuckerman, Lawrence G Lenke, Leah Y Carreon, Kenneth M C Cheung, Michael P Kelly, Michael G Fehlings, Christopher P Ames, Oheneba Boachie-Adjei, Mark B Dekutoski and 8 more

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Observational
  2. Review
  3. Surgical planning for spinal deformity correction: the contribution of patient-specific rods.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Meghan CerpaDepartment of Orthopaedic Surgery, New York Presbyterian, The Daniel and Jane Och Spine Hospital, Columbia University Medical Center, Broadway, New York, NY, 5141, 10034, USA.
Scott L ZuckermanVanderbilt Univerity Medical Center, Nashville, TN, USA.
Lawrence G LenkeDepartment of Orthopaedic Surgery, New York Presbyterian, The Daniel and Jane Och Spine Hospital, Columbia University Medical Center, Broadway, New York, NY, 5141, 10034, USA. ll2989@cumc.columbia.edu.ORCID 0000-0002-5595-4958
Leah Y CarreonNorton Leatherman Spine Center, Louisville, KY, USA.
Kenneth M C CheungLi Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
Michael P KellyRady's Children's Hospital, San Diego, CA, USA.
Michael G FehlingsUniversity of Toronto and Toronto Western Hospital, Toronto, ON, Canada.
Christopher P AmesUniversity of California San Francisco, San Francisco, CA, USA.
Oheneba Boachie-AdjeiThe FOCOS Hospital, Pantang, Pantang West, Republic of Ghana.
Mark B DekutoskiMarshfield Clinic Eau Claire Center, Eau Claire, WI, USA.
Khaled M KebaishJohns Hopkins University, Baltimore, MD, USA.
Stephen J LewisUniversity of Toronto and Toronto Western Hospital, Toronto, ON, Canada.
Yukihiro MatsuyamaHamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Ferran PelliséHospital Universitari Vall d'Hebron, Barcelona, Spain.
Yong QiuAffiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Frank J SchwabHospital for Special Surgery, New York, NY, USA.
Justin S SmithUniversity of Virginia, Charlottesville, VA, USA.
Christopher I ShaffreyDuke University Medical Center, Durham, NC, USA.

Funding

AOSpine AOSpineScoliosis Research Society Scoliosis Research Society
6 · The paper itself

Abstract

purposeTo report all complications that occurred during the 2 to 5-year postoperative period, describe reoperations during this time period, and compare patients who did and did not have major, surgery-related complications and/or reoperations during this time period.

methodsThe Scoli-RISK-1 study enrolled 272 ASD patients undergoing surgery from 15 centers. Inclusion criteria were Cobb angle of > 80°, corrective osteotomy for congenital/revision deformity, and/or 3-column osteotomy. At each follow-up visit, any neurologic or non-neurologic adverse event(AE) was documented & categorized.

results77 patients had a minimum 5-year follow-up. 35 surgery-related AE's occurred during the 2 to 5-year period in 25(32.5%) patients. 23/35(65.7%) major, surgery-related complications occurred in 17 patients, 22/35(62.9%) requiring reoperations in 16 patients. Rod fracture and/or pseudarthrosis was the most common complication. The most common minor, surgery-related complication was asymptomatic rod fractures with no alignment changes. Four neurological complications were reported, one of which did not require reoperation. One death occurred at 6.1 years postoperative after multiple reoperations for mechanical complications. 14/17(82.4%) patients with major, surgery-related complication had a preceding AE during the initial 2-year postoperative period. 53 non-surgery-related AEs occurred in 21(27.3%) patients with musculoskeletal(37.7%) occurring most often. No differences were observed in ODI or SRS-22r in those with/without major surgery-related complications or those with/without reoperation.

conclusionDuring the study period, 25(32.5%) patients experienced 35 surgery-related complications, of which 23(65.7%) were major. Rod fracture with pseudarthrosis was the most common major, surgery-related complication. Neurologic complications were not found to be major drivers of reoperation. Surprisingly, PROs were similar in those with/without a major, surgery-related complication during the study period. This work has been presented as a podium presentation at the 55th Scoliosis Research Society annual meeting, Sep 9-13, 2020.

Indexed as

OsteotomyPostoperative ComplicationsScoliosisSpinal FusionAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedNervous System DiseasesReoperationYoung AdultAdult spinal deformityMechanical complicationsNon-neurologic complicationsPostoperative complicationsScoli-RISK-1Spinal deformity surgery

Identifiers

PMID39937191

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.