Evidence map›Paper›PMID 39936946›Full record

ReviewCells2025

Emerging Insights into Sall4's Role in Cardiac Regenerative Medicine.

Jianchang Yang

Abstract readReview
In one paragraph

Review in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jianchang YangMichael E. DeBakey Department of Surgery, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

Funding

In Situ Cardiac Infarct Cellular ReprogrammingR01HL121294 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI ROSENGART, TODD K · 2015 to 2018
$2.7M
Cell Plasticity-Based Reprogramming Strategies to Enhance Human Myocardial RegenerationR01HL152280 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI ROSENGART, TODD K · 2020 to 2023
$2.5M
NHLBI NIH HHS R01 HL121294NHLBI NIH HHS R01 HL152280
6 · The paper itself

Abstract

Sall4 as a pivotal transcription factor has been extensively studied across diverse biological processes, including stem cell biology, embryonic development, hematopoiesis, tissue stem/progenitor maintenance, and the progression of various cancers. Recent research highlights Sall4's emerging roles in modulating cardiac progenitors and cellular reprogramming, linking its functions to early heart development and regenerative medicine. These findings provide new insights into the critical functions of Sall4 in cardiobiology. This review explores Sall4's complex molecular mechanisms and their implications for advancing cardiac regenerative medicine.

Indexed as

HeartRegenerative MedicineTranscription FactorsAnimalsHumansSALL4 protein, humanTranscription Factorscardiac fibroblastcardiogenicepigenetic regulationmyocardial infarctionpartial reprogrammingprotein interactions

Identifiers

PMID39936946
PMCPMC11817359

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.