Evidence map›Paper›PMID 39936815›Full record

ArticleCoDAS2025

Is there a decline in speech and swallowing in Amyotrophic Lateral Sclerosis over ten years?

Regiani Alabarces Mendes, Ivonaldo Leidson Barbosa Lima, Mário Emílio Teixeira Dourado Júnior, Maria de Jesus Gonçalves

Abstract read
In one paragraph

Article in CoDAS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Regiani Alabarces MendesDepartamento de Fonoaudiologia, Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte - UFRN - Natal (RN), Brasil.ORCID http://orcid.org/0009-0004-7364-5640
Ivonaldo Leidson Barbosa LimaDepartamento de Fonoaudiologia, Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte - UFRN - Natal (RN), Brasil.ORCID http://orcid.org/0000-0003-1716-1575
Mário Emílio Teixeira Dourado JúniorDepartamento de Medicina Integrada, Universidade Federal do Rio Grande do Norte - UFRN - Natal (RN), Brasil.ORCID http://orcid.org/0000-0002-9462-2294
Maria de Jesus GonçalvesDepartamento de Fonoaudiologia, Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte - UFRN - Natal (RN), Brasil.ORCID http://orcid.org/0000-0003-2580-485X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo analyze the evolution of speech and swallowing decline in patients with amyotrophic lateral sclerosis (ALS) over a ten-year period.

methodsA retrospective and longitudinal cohort study. Data were collected using the Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R) from 101 medical records of ALS patients treated at the multidisciplinary neuromuscular diseases clinic of a University Hospital over a ten-year period. The data were statistically analyzed, adopting a significance level of p<0.05.

resultsThe analysis of the studied functions indicated that speech, swallowing, and salivation are altered over ten years in ALS. There are differences in patterns between the variables sex and disease type concerning symptoms related to dysarthria and dysphagia in these individuals, which may indicate the rate of progression over a given time interval.

conclusionThere is a decline in speech and swallowing over ten years in ALS. The bulbar type leads to a faster decline in the studied functions than the spinal type.

Indexed as

Amyotrophic Lateral SclerosisDeglutition DisordersSpeech DisordersAdultAgedAged, 80 and overDeglutitionDisease ProgressionDysarthriaFemaleHumansLongitudinal StudiesMaleMiddle AgedRetrospective StudiesTime Factors

Identifiers

PMID39936815
PMCPMC11813176

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