Evidence map›Paper›PMID 39936542›Full record

Observational studyJournal of comparative effectiveness research2025

Clinical characteristics and treatment outcomes in multiple sclerosis patients treated with anti-CD20s who switched to fumarates: a retrospective analysis of a US healthcare claims database.

Aliza B Ben-Zacharia, Jenny J Feng, Brandon P Moss, Nicholas Belviso, Yu Zhang, Filipe Branco, Jason P Mendoza, James B Lewin, Sarah M England

Abstract readObservational Study
In one paragraph

Observational study in Journal of comparative effectiveness research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aliza B Ben-ZachariaHunter College, Bellevue School of Nursing, NY 10010, USA.ORCID 0000-0002-3174-8244
Jenny J FengOchsner Medical Center, New Orleans, LA 70121, USA.ORCID 0000-0003-3700-7823
Brandon P MossMellen Center for Multiple Sclerosis, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0001-5319-5129
Nicholas BelvisoBiogen, Cambridge, MA 02142, USA.
Yu ZhangFormerly: Biogen, Cambridge, MA 02142, USA.
Filipe BrancoFormerly: Biogen, Baar, Switzerland.
Jason P MendozaBiogen, Cambridge, MA 02142, USA.ORCID 0000-0003-2526-5542
James B LewinBiogen, Cambridge, MA 02142, USA.ORCID 0000-0002-2352-9113
Sarah M EnglandBiogen, Cambridge, MA 02142, USA.ORCID 0009-0008-0232-278X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug SubstitutionFumaratesMultiple SclerosisRituximabAdultDatabases, FactualFemaleHealth Care CostsHumansInsurance Claim ReviewMaleMiddle AgedPropensity ScoreRecurrenceRetrospective StudiesTreatment OutcomeFumaratesRituximabanti-CD20 monoclonal antibodiesde-escalationfumarateshealthcare costshealthcare encountersmultiple sclerosisswitching

Identifiers

PMID39936542
PMCPMC11864085

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.