Evidence map›Paper›PMID 39936459›Full record

ArticleJournal of cosmetic dermatology2025

Nasal Reshaping Using Barbed Threads Combined With Hyaluronic Acid Filler and Botulinum Toxin A.

G Ziade, R Saade, D Daou, D Karam, A Bendito, M Tsintsadze

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

G ZiadeDepartment of Otolaryngology-Head and Neck Surgery, Lebanese American University School of Medicine, Beirut, Lebanon.
R SaadeDepartment of Otolaryngology-Head and Neck Surgery, Lebanese American University School of Medicine, Beirut, Lebanon.
D DaouDepartment of Anesthesia, American University of Beirut Medical Center, Beirut, Lebanon.
D KaramFaculty of Medicine, Holy Spirit University of Kaslik, Jounieh, Lebanon.
A BenditoMartina Children's Hospital, Stockholm, Sweden.
M TsintsadzeFaculty of Medicine, BAU International University Batumi, Batumi, Georgia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRhinoplasty is a prominent procedure in facial aesthetics, but extended surgical downtime remains its significant limitation. Nonsurgical rhinoplasty has gained popularity as an alternative, offering significant aesthetic improvements with minimal downtime. This study evaluates the clinical efficacy and safety of three nonsurgical rhinoplasty techniques combined, including hyaluronic acid (HA) filler, botulinum toxin type A (BTX), and barbed lifting threads.

methodsA total of 85 patients were included into three groups: 63 subjects received HA filler and BTX injections, 9 subjects received barbed threads followed by BTX injections, and 13 received threads followed by HA filler and BTX injections. Patients assessed their satisfaction 1 month and a year posttreatment as well as adverse effects 48 h and 1 week after treatment using FACE-Q questionnaire for nose.

resultsBoth 1 month and a year after treatment, the triple combination of barbed threads with HA filler and BTX demonstrated superior nose FACE-Q scores compared to the two other groups, showing highest patient satisfaction and minimal efficacy decay over time. No significant difference in FACE-Q scores was observed between the two groups receiving HA filler + BTX and barbed threads + BTX at either 1 month or a year posttreatment. Adverse effects were reported by subjects in all three groups 48 h posttreatment and completely resolved by 1 week after treatment.

conclusionCombining nonsurgical rhinoplasty techniques-such as lifting threads, HA fillers, and botulinum toxin-can deliver effective aesthetic improvements with minimal downtime. Among these, the triple combination of HA filler, BTX, and lifting threads results in the highest and most sustained patient satisfaction, lasting no less than 1 year.

Indexed as

Botulinum Toxins, Type ADermal FillersHyaluronic AcidRhinoplastyAdultEstheticsFemaleHumansMaleMiddle AgedNeuromuscular AgentsNosePatient SatisfactionTreatment OutcomeBotulinum Toxins, Type ADermal FillersHyaluronic AcidNeuromuscular AgentsAptos threadsbotulinum toxinhyaluronic acidnoninvasivepoly‐l‐lactic acidrhinoplasty

Identifiers

PMID39936459
PMCPMC11816005

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.