Evidence map›Paper›PMID 39936410›Full record

ReviewAnti-cancer agents in medicinal chemistry2025

An Insight into Research Advances on Herbal and Phytochemical Approaches to the Management of Hepatocellular Carcinoma from January 2020 to July 2024.

Zulfa Nooreen, Sunil Harer, Awani Kumar Rai, Ankita Wal, Deepak Nathiya, Parjinder Kaur

Abstract readReview
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In one paragraph

Review in Anti-cancer agents in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zulfa NooreenPSIT-Pranveer Singh Institute of Technology (Pharmacy), Bhautipratapur, Uttar Pradseh, Kanpur, 209305, India.ORCID 0000-0002-1556-3872
Sunil HarerSchool of Pharmacy, D Y Patil University, Neul East, Nani Mumbai, Maharashtra, 410506, India.
Awani Kumar RaiPSIT-Pranveer Singh Institute of Technology (Pharmacy), Bhautipratapur, Uttar Pradseh, Kanpur, 209305, India.
Ankita WalPSIT-Pranveer Singh Institute of Technology (Pharmacy), Bhautipratapur, Uttar Pradseh, Kanpur, 209305, India.
Deepak NathiyaDepartment of Pharmacy Practice, Institute of Pharmacy, NIMS University, Rajasthan, Jaipur, India.
Parjinder KaurChandigarh Pharmacy College, Chandigarh Group of Colleges, Jhanjeri, Mohali, Punjab, 140307, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatocellular Carcinoma (HCC) is a primary hepatic tumor and is one of the world's third most frequent malignancies after lung and colorectal. After stomach, lung, and colorectal cancers, it is the most common cause of cancer-related mortality. Since the Palaeolithic era, herbs have been used as an essential source of alternative drugs. Modern cancer treatments that use chemotherapeutic medications are made of chemicals derived from plants.

objectiveThe present review is about the compilation of phytochemical extracts and molecules from 2020 to July 2024.

methodsA detailed literature survey was conducted to compile data from PubMed, Sci Finder, Science Direct, Google, etc. Results: The identification of novel treatments and their combinations for usage in the adjuvant context potentially address significant unmet needs in the management of HCC. A large number of investigations have been carried out these days on plants. Numerous phytochemicals included in plant extract may possess anti-cancer properties, including the ability to induce cell cycle arrest, suppress cell proliferation, increase apoptosis, and obstruct migration, invasion, and metastasis. These approaches possess less hazardous and more effective treatment in HCC.

conclusionThis article is the compilation of data about research on phytomolecules and herbal extracts from January 2020 to July 2024 for the treatment of HCC

Indexed as

Antineoplastic Agents, PhytogenicCarcinoma, HepatocellularLiver NeoplasmsPhytochemicalsPlant ExtractsAnimalsApoptosisCell ProliferationDrug Screening Assays, AntitumorHumansAntineoplastic Agents, PhytogenicPhytochemicalsPlant Extractshepatic tumorHepatocellular carcinomaherbal extracts.modern cancer treatmentsphytochemicalsplant extract

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.