Evidence map›Paper›PMID 39936369›Full record

ArticleEuropean journal of ophthalmology2025

Faricimab efficacy in a poorly responsive case of Polypoidal Choroidal Vasculopathy (PCV): A case report.

Clara Rizzo, Maria Cristina Savastano, Raphael Kilian, Stanislao Rizzo

Abstract readCase Reports
In one paragraph

Article in European journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Clara RizzoOphthalmic Unit, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.ORCID 0000-0002-5156-5314
Maria Cristina SavastanoOphthalmology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID 0000-0003-1397-4333
Raphael KilianDepartment of Traslational Medicine, University of Ferrara, Ferrara, Italy.ORCID 0000-0001-7410-8805
Stanislao RizzoOphthalmology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PurposeTo evaluate anatomical and functional outcomes of Faricimab therapy on a case of polypoidal choroidal vasculopathy (PCV) refractory to previous treatments.Major findingsA 56-year-old patient with PCV presenting with a large pigment epithelial detachment (PED) showed best-corrected visual acuity (BCVA) improvement, subretinal fluid (SRF) reduction and PED height reduction at 2 months follow up after a loading phase of 4 monthly Faricimab injections. The patient had previously undergone Aflibercept, Brolucizumab and photodynamic therapy (PDT) treatments with a suboptimal response.ConclusionDespite Faricimab proving itself as an efficient alternative in a case of PCV poorly responsive to previous treatments, definite evidence still needs to be confirmed in larger studies.

Indexed as

ChoroidChoroid DiseasesPolypsAngiogenesis InhibitorsAntibodies, BispecificFluorescein AngiographyFundus OculiHumansIntravitreal InjectionsMiddle AgedPolypoidal Choroidal VasculopathyTomography, Optical CoherenceTreatment OutcomeVascular Endothelial Growth Factor AVisual AcuityAngiogenesis InhibitorsAntibodies, BispecificfaricimabVascular Endothelial Growth Factor Aanti-VEGF therapyFaricimabPCVPED

Identifiers

PMID39936369
PMCPMC12012268

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.