ReviewJournal of cosmetic dermatology2025
Lip Filler Versus "Lip Flip": Longitudinal Public Interest and a Brief Review of Literature.
Review in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The lip flip: a systematic review of botulinum toxin lip augmentation.Archives of dermatological research · 2025Pooled it
- Public Interest in Stress-Induced Dermatologic Conditions and Psychodermatologic Disorders Before, During, and After the COVID-19 Pandemic: Segmented Regression Analysis.JMIR dermatology · 2026Article
- A Psychological Guide to Lower Face Botulinum Toxin Injections: Baseline Emotional Functions of Facial Expressions.Journal of cosmetic dermatology · 2026Review
- Botulinum Toxin for Lip Inversion in Gummy Smile.Cureus · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe lip augmentation market is projected to reach a value of 11.6 billion USD by 2030. Hyaluronic acid (HA) fillers are the most common type due to biocompatibility and reversibility. However, there has been an increase in alternative procedures, such as the "lip flip," involving the injection of botulinum neurotoxin A (BoNT-A) into the superior orbicularis oris muscle.
aimsThe purpose of this study is to review the current literature and evaluate the general public interest in dermal lip fillers compared to supralabial BoNT-A injections over the past decade.
methodsThe Google Trends database was used to collect relative monthly search volume for the terms "lip filler" and "lip flip" over a decade-long period (January 1, 2014-January 1, 2024). Google Trends data is automatically normalized with a value of 100 indicating maximal search volume and 1 indicating minimal search volume.
resultsSearch volume for lip filler and lip flip increased similarly from 2014 to 2024. Lip filler was consistently more searched and had an average 75% increase in relative search volume per month. Meanwhile, "lip flip" had, on average, a 33% increase in search volume per month.
conclusionsAlthough lip filler was more frequently inquired about than "lip flip," the latter increased in popularity over time, reaffirming its popularity as a potential alternative to lip filler. Superior obicularis oris BoNT-A injections are rising in popularity and may be a valuable option for patients seeking cosmesis with hesitation toward dermal fillers.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.