Evidence map›Paper›PMID 39936137›Full record

ArticleTransplantation direct2025

Women and People From Deprived Areas Are Less Likely to be Assessed for Liver Transplantation for Alcohol-related Liver Disease: Results From a National Study of Transplant Assessments.

Christopher Oldroyd, Varuna Aluvihare, Andrew Holt, Yun Chew, Steven Masson, Richard Parker, Neil Rajoriya, Jennifer Ryan, Liz Shepherd, Kenneth Simpson and 5 more

Abstract read
In one paragraph

Article in Transplantation direct, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Christopher OldroydLiver Unit, NIHR Cambridge Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0002-4934-8345
Varuna AluvihareInstitute of Liver Studies, King's College Hospital NHS Foundation Trust, London, United Kingdom.
Andrew HoltLiver Transplant Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.
Yun ChewLiver Unit, The Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.
Steven MassonLiver Unit, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom.
Richard ParkerLiver Unit, The Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.
Neil RajoriyaLiver Transplant Unit, University Hospitals Birmingham NHS Foundation Trust, Institute of Immunotherapy and Inflammation, University of Birmingham, Birmingham, United Kingdom.
Jennifer RyanThe Sheila Sherlock Liver Unit, Royal Free London NHS Foundation Trust, London, United Kingdom.
Liz ShepherdThe Sheila Sherlock Liver Unit, Royal Free London NHS Foundation Trust, London, United Kingdom.
Kenneth SimpsonScottish Liver Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
Clare WaiCambridge and Peterborough NHS Foundation Trust, Cambridge Liver Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Ian WebzellInstitute of Liver Studies, King's College Hospital NHS Foundation Trust, London, United Kingdom.
Sharon WaltonOffice for Health Improvement and Disparities, London, United Kingdom.
Julia VerneKing's College London, London, United Kingdom.
Michael E D AllisonLiver Unit, NIHR Cambridge Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust, University of Cambridge, Cambridge, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Alcohol-related liver disease (ArLD) is the most common indication for liver transplantation in Europe and the United States. Few studies have examined the characteristics of patients with ArLD formally assessed for liver transplants. Methods: We collected prospective data on every patient with ArLD formally assessed for liver transplantation in the United Kingdom during a 12-mo period. Results: Five hundred forty-nine patients with ArLD were assessed for liver transplantation. The median Model for End-Stage Liver Disease (MELD) score was 15 and the UK MELD score was 54. 24% were women. The median duration of abstinence was 12 mo. Listing outcomes were 59% listed, 4% deferred, and 37% not listed. The reasons for not listing were medical comorbidities (29%), too early for transplantation (20%), potential recoverability (18%), recent alcohol use (12%), and other (21%). Patients listed for transplant had a higher median MELD (16 versus 13; Conclusions: This study provides the first complete national profile of evaluations for liver transplantation for patients with ArLD. Women and patients from the most deprived deciles of the population may be relatively underrepresented.

Identifiers

PMID39936137
PMCPMC11809985

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.