Evidence map›Paper›PMID 39936039›Full record

ArticleInfection and drug resistance2025

Antimicrobial Activity and Metabolomic Analysis of Linalool Against Pathogenic Bacteria Methicillin-Resistant

Nana Long, Min Qiu, Youwei Zuo, Hongping Deng

Abstract read
In one paragraph

Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Ethnobotany, Phytochemistry, and Pharmacological Activities ofInternational journal of molecular sciences · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nana LongCenter for Biodiversity Conservation and Utilization, School of Life Sciences, Southwest University, Beibei, Chongqing, People's Republic of China.ORCID 0000-0002-6000-9942
Min QiuSchool of Laboratory Medicine, Chengdu Medical College, Chengdu, Sichuan, People's Republic of China.
Youwei ZuoCenter for Biodiversity Conservation and Utilization, School of Life Sciences, Southwest University, Beibei, Chongqing, People's Republic of China.
Hongping DengCenter for Biodiversity Conservation and Utilization, School of Life Sciences, Southwest University, Beibei, Chongqing, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The purpose of this study was to evaluate the antibacterial activity and mechanism of linalool against Methicillin-resistant Methods: The determination of the antibacterial activity of linalool against clinically isolated MRSA strains was based on the minimum inhibitory concentration (MIC) and growth curve analysis. Finally, the inhibition mechanism of linalool was elucidated through metabolomic analysis and molecular docking. Results: Among the isolated strains, penicillin resistance was found to be the highest, while resistance to daptomycin/quinupristin-dalfopristin, linezolid, vancomycin, tetracycline, telithromycin, and levofloxacin was not observed. The MIC range of linalool was 211.24-1.65 μg/mL, with MIC Conclusion: This study suggests that linalool could be developed as a drug or preservative to inhibit MRSA growth.

Indexed as

antimicrobial resistanceglutathionelinaloolmetabolomeMRSA

Identifiers

PMID39936039
PMCPMC11812441

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.