Evidence map›Paper›PMID 39935989›Full record

ArticleSpine surgery and related research2025

Trabecular Bone Remodeling after Lateral Lumbar Interbody Fusion: Indirect Findings for Stress Transmission between Vertebrae after Spinal Fusion Surgery.

Naoki Segi, Hiroaki Nakashima, Sadayuki Ito, Jun Ouchida, Ryotaro Oishi, Ippei Yamauchi, Yuichi Miyairi, Yoshinori Morita, Mikito Tsushima, Hiroyuki Tomita and 4 more

Abstract read
In one paragraph

Article in Spine surgery and related research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Absence of bone marrow edema on early postoperative MRI predicts fusion outcome after single-level lumbar interbody fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Naoki SegiDepartment of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hiroaki NakashimaDepartment of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Sadayuki ItoDepartment of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Jun OuchidaDepartment of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Ryotaro OishiDepartment of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Ippei YamauchiDepartment of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yuichi MiyairiDepartment of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yoshinori MoritaDepartment of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Mikito TsushimaDepartment of Orthopedic Surgery, Konan Kosei Hospital, Konan, Japan.
Hiroyuki TomitaDepartment of Orthopedic Surgery, Konan Kosei Hospital, Konan, Japan.
Kazuaki MorishitaDepartment of Orthopedic Surgery, Konan Kosei Hospital, Konan, Japan.
Kazuma OhshimaDepartment of Orthopedic Surgery, Konan Kosei Hospital, Konan, Japan.
Tokumi KanemuraDepartment of Orthopedic Surgery, Konan Kosei Hospital, Konan, Japan.
Shiro ImagamaDepartment of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: After posterior lumbar interbody fusion (PLIF), trabecular bone remodeling (TBR) occurs in the vertebral body. This study aimed to investigate whether imaging findings obtained with PLIF are applicable to lateral lumbar interbody fusion (LLIF). Methods: A total of 53 cases who underwent one- or two-level LLIF with polyether ether ketone cage and posterior spinal fixation/fusion (PSF) were retrospectively included in this study. TBR, vertebral endplate cyst (VEC), facet union, and pseudarthrosis were investigated on computed tomography (CT) images at 3 months, 1 year, and 2 years postoperatively. Of the 53 patients, 36 (68%) who underwent CT examination at approximately 5 years postoperatively were subanalyzed. Results: TBR was commonly observed anterior to the cage on CT sagittal images. The TBR-positive rate was 21%, 67%, and 73% at 3 months, 1 year, and 2 years postoperatively, respectively. The 3-month TBR-positive segments showed significantly less VEC (0% vs. 29%, Conclusions: TBR-positive segments had significantly lower future VEC positivity, higher future facet union rates, and lower future pseudarthrosis rates. In LLIF-PSF, TBR suggests the establishment of intervertebral stability and allows consideration of intervertebral biomechanics.

Indexed as

lateral lumbar interbody fusionosseointegrationpolyether ether ketonetrabecular bone remodelingvertebral endplate cyst

Identifiers

PMID39935989
PMCPMC11808242

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.