ReviewIranian endodontic journal2025
Vital Pulp Therapy: Evidence-Based Techniques and Outcomes.
Review in Iranian endodontic journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07073573 (The Relationship Between Pulpal Biomarker Levels and the Success of Vital Pulp Therapy), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Relationship Between Pulpal Biomarker Levels and the Success of Vital Pulp Therapy: A Prospective Clinical Study
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Partial pulpotomy for carious pulp exposure in adult mature permanent teeth: a systematic review and meta-analysis.BMC oral health · 2025Pooled it
- Twenty-four-month outcomes of full pulpotomy in permanent molars with symptomatic irreversible pulpitis: a randomized controlled trial of adjunctive cryotherapy.Clinical oral investigations · 2026Trial
- A regenerative strategy for vital pulp therapy: Platelet-rich fibrin augments stem cell viability and pluripotency in bioactive cement environments.Biochemistry and biophysics reports · 2026Article
- Establishment of an MRI-Based Diagnostic Approach to Identify Critical Pulpal Inflammation Zones in a Rat Caries-Derived Pulpitis Model.International endodontic journal · 2026Article
- Extracellular Matrix-Based and Extracellular Matrix-Bioinspired Scaffolds for Extracellular Vesicle Delivery in Dental Pulp Regeneration: A Narrative Review.Biotech (Basel (Switzerland)) · 2026Review
- The Shear Bond Strength Between Calcium Silicate-Based Biomaterials and Glass Ionomer Restorative Materials: An In Vitro Comparative Study.Journal of functional biomaterials · 2026Article
- Survival of indirect pulp capping in deeply carious primary molars under local versus general anesthesia: a retrospective cohort study using propensity score matching.BMC oral health · 2026Article
- Clinical outcomes of vital pulp therapy versus root canal treatment in immature permanent teeth with pulpal involvement: a meta-analysis.Frontiers in pediatrics · 2026Article
- Direct Clinical Evidence of Long-term Hard-tissue Repair after Miniature/Tampon Pulpotomy: An Accidental Re-entry Case after Six Years.Iranian endodontic journal · 2026Article
- Intraoperative Identification of Vital Radicular Pulp in a Tooth Diagnosed with Pulp Necrosis: Four-Year Outcome of Tampon Pulpotomy.Iranian endodontic journal · 2026Article
- Osteogenic Response of Saos-2 Cells to Calcium Silicate-based versus Hydroxyapatite-based Cements: A Comparative Study.Iranian endodontic journal · 2026Article
- Cytocompatibility of Three Calcium Silicate-Based Biomaterials: A Systematic Review and Meta-Analysis.Iranian endodontic journal · 2026Review
- Managing limited clinical crown height with vital pulp therapy: Clinical application and outcome.Journal of dental sciences · 2025Article
- Cytotoxicity of Calcium Silicate-Based Cements: Role of Bonding Time, Strategy, and Thickness in an In Vitro Model.Iranian endodontic journal · 2025Article
- Comparative evaluation of post-operative pain following single vs. multiple visit pulpectomy: A clinical assessment.Bioinformation · 2025Article
- A Critical Review of the Role of Geristore® in Contemporary Endodontics.Iranian endodontic journal · 2025Review
- Paresthesia and Dysesthesia after Root Canal Therapy of a Mandibular Molar: Diagnosis and Management in a Clinical Case Report.Iranian endodontic journal · 2025Article
- The Impact of Vital Pulp Therapy on Normal Root Development in Immature Teeth: A Case Report.Iranian endodontic journal · 2025Article
- Partial Pulpectomy with Bio-Obturation for Internal Root Resorption: A Case Report.Iranian endodontic journal · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vital pulp therapy (VPT) comprises a range of conservative treatment modalities aimed at preserving the vitality of the compromised dental pulp in primary and permanent teeth. This PubMed-based review comprehensively evaluates seven distinct VPT techniques; including their historical development, broad definitions, clinical protocols and treatment outcomes as evidenced by systematic reviews and meta-analyses. The VPT modalities covered in this review include stepwise excavation, indirect pulp capping, direct pulp capping, miniature pulpotomy, partial pulpotomy, full pulpotomy and partial pulpectomy. Stepwise excavation, as a minimally-invasive option, has demonstrated effectiveness in reducing the risk of pulp exposure, particularly in permanent teeth. Clinical outcomes of indirect and direct pulp capping are promising; specifically with the application of advanced calcium silicate cements. Miniature and partial pulpotomies emphasize the importance of precise definitions and standardised protocols due to their subtle differences. Full pulpotomy has emerged as a viable alternative to root canal treatment, achieving comparable success rates in managing irreversible pulpitis. While partial pulpectomy remains the most invasive approach, it has shown potential in managing complex cases, such as root resorption, through selective tissue preservation. Despite advancements in biomaterials and technique standardisation, challenges remain, including variability in clinical protocols, limited high-quality evidence, and the need for long-term studies to better evaluate anticipated outcomes. Nevertheless, emerging biotechnologies hold promise for enhancing the precision and predictability of VPT procedures in the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.