ArticleHealth science reports2025
Prevalence of HSV-1/HSV-2 and CMV Infections in Infertile Men and Their Impact on Sperm Parameters: A Cross-Sectional Study in Iran.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Viral infections are significant contributors to infertility. This study aimed to determine the prevalence of Herpes Simplex Virus 1 and 2 (HSV-1/HSV-2) and cytomegalovirus (CMV) infections in men with infertility, compared to a control group of fertile men. Methods: A cross-sectional study was conducted with seminal fluid samples from 100 fertile and 100 infertile men, aged 20-40 years, referred to Yazd Infertility Center. DNA extraction was done using the AmpliSens kit, and the presence of CMV and HSV-1/HSV-2 was determined via real-time PCR. Sperm parameters (count, quick & slow, motility, morphology, and volume) were also assessed and compared to the control group. Results: CMV infection was found in 16% of fertile and 10% of infertile men. HSV-1/HSV-2 prevalence was significantly higher in infertile men (32%) compared to fertile men (8%). Abnormal sperm count was significantly associated with HSV status ( Conclusion: HSV infection is linked to sperm-specific parameters, particularly count and morphology. These findings enhance our understanding of viral-induced male infertility and underscore the need for targeted approaches to manage HSV-1/HSV-2-related infertility.
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